US 8,802,687 B2Granted

Cadherin-11 inhibitors and methods of use thereof

AssigneeGeorgetown University

InventorsStephen W. Byers, Sivanesan Dakshanamurthy, Jaime M. Guidry Auvil, Milton L. Brown

Life of this patent

Estimating the term…

Abstract

Cadherin-11 inhibitors, including 4-(2-phenylpyridin-3-yl)phenol, and methods for the prevention and treatment of cadherin-11 related diseases are described herein. Cadherin-11 related diseases include cancer and rheumatoid arthritis.

Claims3

Dependent claims

A compound of the following formula:

or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 13/148,579Filed 9 Feb 2010 · us provisional application
Priority: 9 Feb 2009
Published: US 2012/0128693 A124 May 2012
Granted: 12 Aug 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

A61K 31/498
Having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines: pyrazines or piperazines…
A61K 31/343
Having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide: condensed with a carbocyclic ring, e.g. coumaran,…
A61K 31/44
Having six-membered rings with one nitrogen as the only ring hetero atom: non condensed pyridines; Hydrogenated derivatives thereof
A61K 31/473
Quinolines; Isoquinolines: ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines

Family

Application61/151,038Us provisional application · filed 9 Feb 2009
US 2012/0128693 A1Pre-grant publication · published 24 May 2012
US 8,802,687 B2This patent

From the US filing history. Foreign family members aren’t listed.

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