Sulfone-substituted anilinopyrimidine derivatives as CDK inhibitors, the production thereof, and use as a medicine

Compounds of formula (I),

• in which
• R1 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C7-cycloalkyl or phenyl, in each case optionally substituted one or more times, identically or differently, with hydroxy, —NR3R4, cyano, halogen, —CF3, C1-C6-alkoxy, —OCF3 or C1-C6-alkyl,
• R2 is C1-C10-alkyl, C3-C10-alkenyl, C3-C10-alkynyl or C3-C7-cycloalkyl,
• in each case optionally substituted one or more times, identically or differently, with
• a) halogen, hydroxy, —NR3R4, cyano, —CF3, or —OCF3, or
• b) C1-C6-alkoxy, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, —O—CH2-phenyl, or Cn-alkoxycarbonyl,
• in each case optionally substituted themselves one or more times, identically or differently, with halogen, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, —NR3R4, —CF3 or —OCF3,
• R3 and R4 independently of one another, are hydrogen, C1-C6-alkyl, C2-C6-alkenyl, C3-C8-cycloalkyl, phenyl, heterocyclyl having 3 to 8 ring atoms, or monocyclic heteroaryl, optionally substituted one or more times, identically or differently, with hydroxy, —NR5R6, cyano, halogen, —CF3, C1-C6-alkoxy or OCF3,
• or
• R3 and R4 together with the nitrogen atom, form a 5- to 7-membered ring which, optionally, in addition to the nitrogen atom, contains one or two further heteroatoms and which may be substituted one or more times, identically or differently, with hydroxy, —NR5R6, cyano, halogen, —CF3, C1-C6-alkoxy or —OCF3, and
• R5 and R6 independently of one another, are hydrogen or C1-C6-alkyl, which is optionally substituted one or more times, identically or differently, with hydroxy, cyano, halogen, —CF3, C1-C6-alkoxy or —OCF3,
• and salts, diastereomers and enantiomers thereof.