Combination therapy for treatment of sleep apnea
AssigneeVivus, Inc.
InventorThomas Najarian
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Abstract
The present invention features a novel therapy for effecting weight loss which involves treating a subject with a sympathomimetic agent (e.g., phentermine or a phentermine-like drug) in combination with an anticonvulsant sulfamate derivative (e.g., topiramate) such that the subject experiences weight loss. The combination methods of the present invention also are effective against symptoms associated with Syndrome X. The invention also features pharmaceutical compositions and kits for use in the practice of these novel therapies.
Claims25
A method for treating sleep apnea in an obese patient comprising administering to the patient a therapeutically effective amount of a carbonic anhydrase inhibitor comprising an anticonvulsant sulfamate derivative in combination with a therapeutically effective amount of a sympathomimetic agent, wherein the sympathomimetic agent is phentermine.
Dependencies are inferred from the claim text.