Emissive compositions with internal standard and related techniques
AssigneeMassachusetts Institute of Technology
InventorsTimothy M. Swager, Jessica H. Liao
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Abstract
The present invention provides materials, devices, and methods related to determination of an analyte. In some embodiments, an analyte may be determined by monitoring, for example, a change in an optical signal of a luminescent material (e.g., particle) upon exposure to an analyte. The present invention may be particularly advantageous in that some embodiments may comprise an emissive species useful as an internal reference standard. Methods of the invention may also be useful in the quantitative determination of an analyte. In some cases, the present invention may allow for selective determination of an analyte.
Claims23
A particle, comprising:
- a core comprising a polymer that is substantially non-luminescent in the visible region,
- an outer layer at least partially encapsulating the core, wherein the outer layer comprises a luminescent polymer having a pi-conjugated backbone and having a first emission upon exposure to a set of conditions, wherein the pi-conjugated backbone has the structure
- wherein n is at least 1, A and C are aromatic groups, optionally substituted, and B and D are alkene, alkyne, heteroalkene, or heteroalkyne;
- and
- a plurality of luminescent metal species having a second emission upon exposure to said set of conditions, wherein at least a portion of the plurality of metal species is integrally connected to the core.
Dependencies are inferred from the claim text.