Loading patent…
AssigneesUniversite Claude Bernard Lyon I, Inserm (Institut National De La Sante Et De La Recherche Medicale)
InventorRené Ferrera
Estimating the term…
A device for hypothermic perfusion of a cardiac organ comprising a first sealed tank able to contain a physiological liquid, a second sealed tank communicating, in a sealed manner, with an internal volume of the first tank via a nozzle, a device for refrigerating the first tank and keeping the first tank at a substantially constant temperature and a device for intermittently pressurizing the internal volume of the first tank. The first tank communicates with the pressurizing device by way of a conduit connecting an interior of the first tank to the pressurizing device to permit pressurization of the internal volume of the first tank, and of the physiological liquid inside the first tank, in order to perform perfusion of the organ. The second tank comprises a safety element formed by an overflow outlet duct which communicates with the first tank and includes a non-return valve.
A device (1) for hypothermic perfusion of a cardiac organ comprising:
Dependencies are inferred from the claim text.
Drawings are temporarily unavailable. Open the PDF at USPTO
From the US filing history. Foreign family members aren’t listed.
Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving: carriers for immersion in cryogenic…
Apparatus: for organ perfusion
Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving: with provisions specially adapted for…
Preservation of bodies of humans or animals or plants or parts thereof
About 4 years 1 month of term left · ends 8 Dec 2030 (estimated)
The present invention relates to the field of removal and storage of organs with a view to their transplantation, both in humans and in animals.
More particularly, the invention relates to a method for hypothermic perfusion of a cardiac organ and to a perfusion device for carrying out the method.
Organ transplant operations, put simply, involve at least one defective organ in a living patient being replaced by the healthy and functional corresponding organ from a deceased person or, in the case of kidney transplants for example, from a living person who has agreed to donate one of his or her kidneys to a patient who is ill.
In the attached figures:
FIG. 1 shows a perfusion device according to the invention during a “systole” phase of a heart.
FIG. 2 is an illustration similar to that of FIG. 1, but during a “diastole” phase of the heart.
FIGS. 1 and 2 show a preferred embodiment of device 1 for hypothermic perfusion of organs in accordance with the invention. In these two figures, the perfusion device 1 contains an organ O perfused by means of the device 1, this organ being a non-beating heart in the case illustrated. However, the device 1 is not limited to the perfusion of hearts and can also be used for the hypothermic perfusion of other organs.
The perfusion device 1 of the invention has a first sealed tank 2, on which is mounted a second tank 3 which is also sealed and which communicates with the first tank 2 by way of a nozzle 6 forming a cannula to which the organ O to be perfused is attached, the organ O being immersed in a physiological liquid LP contained in the first tank 2.
The first tank 2 also communicates with a pressurizing device 4 by way of a conduit 5 connecting the interior of the first tank 2 to the pressurizing device, so as to permit the pressurization of the internal volume of the first tank 2, and of the physiological liquid inside the latter, in order to perform perfusion of the organ O.