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US 8,802,400 B2Granted
L-lysine-containing feed additives
AssigneeEvonik Degussa GmbH
InventorsHermann Lotter, Ulrich Becker, Frank Dübner, Friederike Kaeppke, Joachim Pohlisch, Ralf Kelle, Cory M. Sander, Lawrence Edward Fosdick
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Abstract
The invention relates to relatively light and thermally stable granulated, fermentation-broth-based animal feed additives having a high content of L-lysine and to low-loss methods for their production from broths obtained by fermentation.
Claims8
Method for producing a granulated L-lysine-containing feed additive comprising
- a) fermenting L-lysine-producing microorganism in an aqueous medium under aerobic conditions to form a fermentation broth containing biomass and L-lysine, thereby completing the fermentation,
- b) determining, when desired, sulphate/L-lysine ratio (V) in the fermentation broth, where V=2×[SO42−]/[L-lysine],
- c) lowering pH by adding sulphuric acid to 4.9 to 5.2,
- d) setting the sulphate/L-lysine ratio to 0.85 to 1.2 by adding ammonium sulphate or sulphuric acid, if necessary, and
- e) granulating the mixture resulting from steps c) and d) to form a product, which granular product has an L-lysine content of 10 to 70% by weight (determined as lysine base, based on the total amount) and a pH of 3.5 to 5.1, measured as a suspension of 10% strength.
2 more elements
Dependencies are inferred from the claim text.