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US 8,802,382 B2Granted
Cobalamin assay
AssigneeAxis-Shield ASA
InventorsLars Orning, Anne Rian
Life of this patent
Estimating the term…
Abstract
The present invention provides a specific binding partner for holoTC having a specificity for holoTC over apoTC of at least 40-fold and an assay method for assaying for holoTC in a sample, the method comprising contacting the sample with a specific binding partner for holoTC and detecting the resultant conjugates.
Claims13
An assay method for assaying for holoTC in a sample, said method comprising contacting said sample with a specific binding partner for holoTC and detecting the resultant conjugates of holoTC and the specific binding partner, wherein:
- said specific binding partner is a specific binding partner for holoTC having a specificity for holoTC over apoTC of at least 40-fold, and
- said specific binding partner also has affinity for at least one constrained peptide comprising the motif SFFYSLCYCW (SEQ ID NO:
- 9), relative to apoTC of at least 40-fold.
Dependencies are inferred from the claim text.