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US 8,802,115 B2Granted
Solid forms for tissue repair
AssigneeCartiheal (2009) Ltd.
InventorsNir Altschuler, Razi Vago
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Abstract
This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.
Claims18
A scaffold for tissue repair, said scaffold consisting essentially of two phases wherein:
- a first phase of said two phases comprises solid coral comprising a biocompatible polymer;
- and
- a second phase of said two phases comprises solid coral and said second phase further comprises a series of hollows along a longitudinal axis in said second phase,
- wherein said first phase does not comprise a series of hollows along a longitudinal axis said second phase does not comprise a biocompatible polymer and said scaffold is cut from or shaped from a single piece of coral, and wherein said biocompatible polymer in said first phase comprises a glycosaminoglycan comprising hyaluronic acid, sodium hyaluronate, cross-linked hyaluronic acid, or a combination thereof.
1 more element
Dependencies are inferred from the claim text.