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US 8,802,072 B2Granted
Biocompatible adhesive materials and methods
AssigneeMassachusetts Institute of Technology
InventorsNatalie Artzi, Elazer R. Edelman, Núria Oliva Jorge, Maria Carcolé Solanes
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Abstract
Biocompatible adhesive materials, such as for use with biological tissues and/or medical implants, are provided, as well as methods and kits for making and using the biocompatible adhesive materials. The biocompatible adhesive materials include a dendrimer component and a polymer component, and may be tailored for specific tissue types and conditions.
Claims23
A method for treating, adhering, or sealing biological tissue, the method comprising:
- providing a first solution comprising a polymer component, wherein the polymer component comprises a polymer having one or more aldehyde groups;
- providing a second solution comprising a dendrimer component, wherein the dendrimer component comprises a dendrimer having at least 2 branches with one or more surface groups, wherein less than 75% of the surface groups comprise at least one primary or secondary amine;
- combining the first and second solutions together to produce an adhesive formulation and contacting one or more biological tissues with the adhesive formulation;
- and
- allowing the adhesive formulation to cure in contact with the one or more biological tissues.
2 more elements
Dependencies are inferred from the claim text.