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US 8,802,008 B2Granted
Dispensing nozzle for automatic analyzer, and automatic analyzer including same
AssigneeHitachi High-Technologies Corporation
InventorsShinichi Taniguchi, Akihiro Nojima
Life of this patent
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Abstract
An automatic analyzer for analyzing samples, such as urine and blood, is adapted so that analysis measured values are not affected by carry over by a repeatedly used dispensing nozzle. Coating the surface of the dispensing nozzle with a chemisorbed polyethylene glycol derivative forms a molecular layer that inhibits the adsorption of biopolymers, to reduce carry over by the dispensing nozzle.
Claims6
An automatic analyzer comprising:
- a plurality of sample containers each containing a sample;
- a plurality of reagent containers each containing a reagent;
- a plurality of reaction Cells into which the samples and the reagents are to be injected;
- a sample dispensing mechanism comprising a sample dispensing nozzle and dispensing the samples in the sample containers into the reaction Cells;
- a reagent dispensing mechanism comprising a reagent dispensing nozzle and dispensing the reagents in the reagent containers into the reaction Cells, and
- electrostatic capacitance measuring means for measuring electrostatic capacitance between the sample dispensing nozzle and the reaction Cell, wherein
- the sample dispensing nozzle has a nozzle main body made of metal, and a silicon oxide layer on an outer surface of the nozzle main body, and a silicon derivative having polyethylene glycol, represented by the following general formula:
- Si—R1—(OCH2CH2)n—O—R2 (n is a positive integer of 2 or more, R1 is a hydrocarbon group, and R2 is H or CH3)
- is chemisorbed on the silicon oxide layer, and
- the electrostatic capacitance measuring means measures the electrostatic capacitance via the silicon oxide layer and the silicon derivative.
7 more elements
Dependencies are inferred from the claim text.