A disposable cassette couplable to a machine for the treatment of a medical liquid, said machine having a coupling surface and a flexible mat arranged on the coupling surface, a measurement chamber arranced in the coupling surface, and a sensor arranged in the measurement chamber, the sensor being configured to detect a deflection of a region of the flexible mat disposed above the measurement chamber, the deflection resulting from a differential pressure between the disposable cassette and the treatment machine, said disposable cassette comprising:
- a thin-walled three-dimensional part having a hard material of construction, and
- liquid conducting passages covered by a flexible film that is couplable to the coupling surface of the treatment machine via the flexible mat,
- with the disposable cassette being configured such that air between the flexible film and the flexible mat is removable in order to provide a vacuum-based coupling of the disposable cassette.