s-Triazine compounds, pharmaceutical compositions and methods of using the same

A s-triazine compound having a formula:

• wherein
• L1 is a single bond, and L2 is C1-C4 alkylene;
• or
• L1 is C1-C4 alkylene, and L2 is a single bond or C1-C4 alkylene;
• L3 is selected from C2-C6 alkylene, C2-C6 alkenyl, and C2-C6 alkynyl;
• each of R1 and R2 is independently substituted or unsubstituted C1-C6 alkyl;
• or
• R1 and R2 may join together to form a 4-7 membered heterocycloalkyl;
• or
• R1 is H;
• and R2 is —C(═NH)—NH2;
• R3 is R4;
• or R3 is selected from substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl;
• R4 is substituted or unsubstituted
• each X is C or N;
• provided that no more than three Xs are N at one time;
• and
• the X through which the R4 is attached to L1 or L2 is C;
• each Y is C or N;
• provided that no more than three Ys are N at one time;
• and
• the Y through which the R4 is attached to L1 or L2 is C;
• R6 is H or substituted or unsubstituted C1-C6 alkyl;
• each R5a, R5b, or R5c is independently H or substituted or unsubstituted C1-C6 alkyl;
• or a pharmaceutically acceptable salt thereof;
• or stereoisomers, or tautomers thereof.