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US 8,796,415 B2Granted
Inhibitors of guanine exchange factors and their use as anticancer drugs
AssigneesCentre National De La Recherche Scientifique, Universite Montpellier 2 Sciences Et Techniques
InventorsAnne Debant, Susanne Schmidt, Nathalie Bouquier, Sylvie Fromont
Life of this patent
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Abstract
A peptide including the amino acids sequence X9CGYX13X14AX16X17X18MX20X21X22X23X24X25X26X27CPLCX32X33, a nucleic acid coding for the peptide, and/or a recombinant vector including the nucleic acid for the preparation of a drug intended for the treatment of cancer.
Claims5
A method for treating cancer, comprising administering to a subject in need thereof a therapeutically effective amount of an isolated peptide comprising the amino acid sequence SEQ ID NO:
- 3
- ICGYX13LAX16X17X18MLGPX23X24RVX27CPLCX32P
- wherein X13, X16, X17, X18, X23, X24, X27 and X32 represent any amino acids, and having at least one of the following features:
- X13 is D;
- X16 is M or A;
- X17 is S;
- X18 is D, G or A;
- X23 is G;
- X24 is A;
- X27 is L;
- and
- X32 is G.
9 more elements
Dependencies are inferred from the claim text.