Method of using β-hydroxy-β-methylbutyrate to treat a condition
AssigneeAbbott Laboratories
InventorsDebra L. Thomas, Pradip Mukerji
Life of this patent
Estimating the term…
Abstract
Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of β-hydroxy-β-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
Claims19
A method of treating an individual having a condition characterized by a higher relative ratio of type 2 cytokines to type 1 cytokines, the method comprising administering to the individual a composition comprising an effective amount of β-hydroxy-β-methylbutyrate to increase the relative ratio of type 1 to type 2 cytokines, wherein said treating consists of at least one of delaying the onset of said condition and reducing the severity of symptoms of said condition, and wherein said condition is selected from the group consisting of allergy and asthma.
Dependencies are inferred from the claim text.