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US 8,796,315 B2Granted
Methods for improved wound closure employing olivamine and human umbilical vein endothelial cells
OwnerDarlene E. McCordinventor
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to compositions for and methods of improving wound healing, including compositions for and methods of treating chronic wounds, and compositions for the inhibition and treatment of necrosis and extended quiescence that result in cellular necrosis instead of normal proliferation. The methods for wound healing administer one or more compositions including hydroxytyrosol and oleuropein with cells derived from umbilical cord blood.
Claims18
A method for accelerating wound closure to improve wound healing comprising:
- administering or transplanting to a subject in need of wound healing a composition comprising an effective amount of hydroxytyrosol and oleuropein and an effective amount of cells derived from umbilical cord blood, wherein the administration of the composition reduces the time required for healing of the wound by at least about 30% in comparison to a composition treated with the cells derived from umbilical cord blood alone.
A method for promoting cellular migration to improve wound healing comprising:
- topically administering or transplanting to a subject in need of wound healing a composition comprising hydroxytyrosol and oleuropein and cells derived from umbilical cord blood;
- and
- reducing the time required for wound healing at least 50% of a wound, as measured by cellular migration to close a wound, to below at least 12 hours.
Dependencies are inferred from the claim text.