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US 8,796,230 B2Granted
Ivermectin antagonizes ethanol inhibition in P2X4 receptors
AssigneeUniversity of Southern California
InventorsDaryl L. Davies, Ronald L. Alkana, Liana Asatryan, Daya I. Perkins, Maya S. Popova
Life of this patent
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Abstract
A method for reducing alcohol consumption in a subject includes a step of identifying a subject exhibiting at least one symptom of alcoholism and then administering a therapeutically effective amount of an Ivermectin analogue-containing composition to the subject. A method of screening Ivermectin analogues for reducing alcohol consumption is also provided.
Claims17
A method for reducing alcohol consumption in a subject, the method comprising:
- identifying a subject exhibiting at least one symptom of alcoholism;
- and
- administering a therapeutically effective amount of an Ivermectin analogue-containing composition to the subject to reduce alcohol consumption wherein the composition is administered for a period of a week to several months, the Ivermectin analogue-containing composition comprising at least one Ivermectin analogue having the following formula:
- wherein R1 is a C1-C10 alkyl.
1 more element
A method for reducing alcohol consumption in a subject, the method comprising:
- identifying a subject exhibiting at least one symptom of alcoholism;
- and
- administering a therapeutically effective amount of Ivermectin to the subject to reduce alcohol consumption wherein the Ivermectin is administered for a period of a week to several months.
Dependencies are inferred from the claim text.