Derivatisation of erythropoietin (EPO)
AssigneeLipoxen Technologies Limited
InventorsGregory Gregoriadis, Sanjay Jain, Peter Laing, Norbert Oskar Rumpf
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Abstract
The present invention relates to a compound which is a polysaccharide derivative of EPO, or of an EPO like protein, wherein the polysaccharide is anionic and comprises between 2 and 200 saccharide units. The present invention also relates to pharmaceutical compositions comprising the novel compounds, and methods for making the novel compounds.
Claims9
A compound which is a polysaccharide derivative of erythropoietin (EPO), wherein the polysaccharide is anionic and comprises between 2 and 125 saccharide units and wherein the EPO is derivatised by the polysaccharide at the reducing terminal unit of the polysaccharide, and wherein the polysaccharide reacts with an amine group of an internal amino acid side chain of EPO.
Dependencies are inferred from the claim text.