β-arrestin effectors and compositions and methods of use thereof
AssigneeTrevena, Inc.
InventorsDennis Yamashita, Xiao-Tao Chen
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Abstract
This application describes a family of compounds acting as β-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
Claims20
A method of treating a cardiovascular disorder in a subject, the method comprising administering to the subject a pharmaceutical composition comprising a peptide comprising SEQ ID NO:
- 27, or a pharmaceutically acceptable salt thereof.
A method of decreasing renal vascular resistance and/or maintaining glomerular filtration rate in a subject, the method comprising administering to the subject a pharmaceutical composition comprising a peptide comprising SEQ ID NO:
- 27, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.