Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
AssigneeRamot at Tel-Aviv University Ltd.
InventorsMeital Reches, Ehud Gazit
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Abstract
A nanostructure composed of a plurality of peptides, each peptide containing at least one aromatic amino acid, whereby one or more of these peptides is end-capping modified, is disclosed. The nanostructure can take a tubular, fibrillar, planar or spherical shape, and can encapsulate, entrap or be coated by other materials. Methods of preparing the nanostructure, and devices and methods utilizing same are also disclosed.
Claims12
An artificial tissue comprising viable cells incorporated throughout a porous biocompatible matrix composed of at least one nanostructure, said at least one nanostructure being selected from the group consisting of a tubular nanostructure and a fibrillar nanostructure, and comprising a plurality of aromatic homodipeptides, wherein at least one of said homodipeptides is an end-capping modified peptide.
A matrix made of at least one nanostructure, said at least one nanostructure being selected from the group consisting of a tubular nanostructure and a fibrillar nanostructure, and comprising a plurality of aromatic homodipeptides, wherein at least one of said homodipeptides is an end-capping modified peptide,
- the matrix being capable of introducing and growing therethrough cells.
Dependencies are inferred from the claim text.