Pre-or post-exposure treatment for filovirus or arenavirus infection
AssigneesTrustees of Boston University, Boston Medical Center Corporation
InventorThomas W. Geisbert
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Abstract
The compositions and methods of the invention described herein provide pre- or post-exposure treatments against filovirus or arenavirus infection by expressing one or more genes (e.g., two ore more genes) from filoviruses or arenaviruses in a delivery vehicle (e.g., a recombinant viral vector or a liposome).
Claims13
A method of inhibiting or treating infection by Sudan species of Ebola virus (SEBOV) in a subject exposed to said SEBOV, said method comprising administering to said subject no later than 30 minutes after infection by said SEBOV a pharmaceutical composition comprising a recombinant viral vector that encodes at least a glycoprotein from said SEBOV, wherein the glycoprotein is heterologous to the viral vector.
Dependencies are inferred from the claim text.