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US 8,795,956 B2Granted
Method for the anti-inflammatory protection of transplants using quercetin glucuronide
AssigneeBoehringer Ingelheim International GmbH
InventorsAnke Esperester, Stephan Nees
Life of this patent
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Abstract
The invention relates to a method for protecting transplants, as well as organs and individual blood vessels, against inflammatory reactions that are caused by the operative procedure linked to the explantation and storage until transplantation. This can be achieved by treating the transplant via intra arterial application of flavonol compounds, in particular with quercetin glucuronide and/or kaempferol glucuronide.
Claims4
Process for protecting transplants from the formation of inflammation in blood vessels, comprising:
- a) removing the transplant,
- b) treating the said transplant with 100 uM of quercetin glucuronide, and
- c) re-implanting the said treated transplant into a recipient body;
- wherein, the transplant is an organ, blood vessels or a combination of both, and wherein each organ, blood vessel or a combination of both has an inner surface and an outer surface.
1 more element
Dependencies are inferred from the claim text.