Surface modification
AssigneeGreiner Bio-One GmbH
InventorHeinrich Jehle
Life of this patent
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Abstract
The invention relates to a carrier comprising at least one substrate, which has a coating in at least certain regions produced from individual modules by plasma polymerization, and the coating has one or more free spaces in at least certain regions for accommodating at least one solution containing a biological sample.
Claims13
Method of modifying at least certain regions of a surface of a carrier, whereby a coating of at least one substrate containing individual modules of at least one monomer species is deposited via plasma polymerization, and free spaces are created in at least certain regions for accommodating at least one solution by activating the surface of the substrate in the plasma before plasma polymerization, wherein activation takes place in a reactor using a reaction mixture containing a carrier gas and a reaction gas, wherein the carrier gas is an inert gas and the reaction gas is selected from the group consisting of oxygen, ammonia, H2, N2, CO2, and C2H2, and wherein activation is conducted at a 9 to 18 times higher power input than plasma polymerization, and generates binding sites, the carrier immobilizing nucleic acids whilst simultaneously repelling proteins.
Dependencies are inferred from the claim text.