# US 8,794,929 B2 · Electrokinetic pump designs and drug delivery systems

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- Number: US 8,794,929 B2
- Document ID: US8794929B2
- Status: Granted
- Kind: B2
- Application number: 11/603,925
- Filed: 2006-11-22
- Published: 2007-06-28
- Granted: 2014-08-05
- Earliest claimed: 2005-11-23
- Assignees: Eksigent Technologies, LLC
- Applicants: Deon Stafford Anex; Charles Martin Schwimmer; David Laurence Black; Richard Dean Rush; Michael James Gearhart
- Inventors: Deon Stafford Anex; Charles Martin Schwimmer; David Laurence Black; Richard Dean Rush; Michael James Gearhart
- Web page: https://patentgrep.com/patent/US8794929B2

## CPC

- F04B 19/04: Pumps for special use
- A61M 5/14526: {the piston being actuated by fluid pressure}
- F04B 17/00: Pumps characterised by combination with, or adaptation to, specific driving engines or motors
- F04B 19/006: {Micropumps (F04B43/043 and F04B43/095 take precedence)}
- A61M 2005/14513: {with secondary fluid driving or regulating the infusion}
- A61M 2209/045: for filling, e.g. for filling reservoirs
- Y10T 137/0391: Affecting flow by the addition of material or energy
- F04B: POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS (machines for liquids, or pumps, of rotary-piston or oscillating-piston type F04C; non-positive-displacement pumps F04D; pumping of fluid by direct contact of another fluid or by using inertia of fluid to be pumped F04F)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

The present invention provides a fluid delivery system having a first chamber, a second chamber and a third chamber; a flow-through pump element separating the first chamber from the second chamber; a moveable pump element separating the second chamber from the third chamber; a first outlet in communication with the third chamber; and second outlet in communication with the second chamber. Additionally, the present invention provides methods of operating a fluid delivery system having a first chamber, a second chamber and a delivery chamber by reducing the volume of the second chamber while increasing the volume of the delivery chamber without operation of a flow-through pump element that separates the second chamber from the first chamber.

## Claims

### Claim 1

A fluid delivery system, comprising:
a housing having a first chamber, a second chamber and a third chamber;
an electrokinetic pump element separating the first chamber from the second chamber, the electrokinetic pump element comprising a porous dielectric material disposed between a pair of electrodes;
a first moveable pump element separating the second chamber from the third chamber;
a second moveable pump element defining a wall of the first chamber;
a pump liquid in the first chamber;
a storage liquid in the second chamber in contact with the flow-through pump element;
a first outlet through a wall in the housing in communication with the third chamber; and a second outlet through a wall in the housing at the second chamber, the second outlet configured to allow the storage liquid in the second chamber to flow therethrough without flowing through the electrokinetic pump element as the first movable element moves towards the second chamber.

### Claim 2 (depends on 1)

The fluid delivery system according to claim 1 wherein the second moveable pump element is a diaphragm.

### Claim 3 (depends on 1)

The fluid delivery system according to claim 1 further comprising: a valve separating the second outlet from an exterior of the housing.

### Claim 4 (depends on 1)

The fluid delivery system according to claim 1 further comprising: a flap separating the second outlet from an exterior of the housing.

### Claim 5 (depends on 1)

The fluid delivery system according to claim 1 further comprising: a valve positioned in the housing that when actuated allows communication between the third chamber and an exterior of the housing and communication between the second chamber and the first chamber.

### Claim 6 (depends on 1)

The fluid delivery system according to claim 1 further comprising an air vent in communication with the first chamber, the second chamber or the third chamber.

### Claim 7 (depends on 1)

The fluid delivery system according to claim 1 wherein a portion of the housing is shaped to conform to an anatomical contour.

### Claim 8 (depends on 1)

The fluid delivery system of claim 1, wherein the fluid delivery system is configured such that a volume of the second chamber reduces and a volume of the third chamber increases during removal of the storage fluid from the second chamber.

### Claim 9 (depends on 1)

The fluid delivery system of claim 1, wherein the fluid delivery system is configured such that a delivery fluid can be filled into the third chamber while storage liquid is removed from the second chamber.

### Claim 10 (depends on 9)

The fluid delivery system of claim 9, wherein the fluid delivery system is further configured such that, in operation, the electrokinetic pump element is configured to move the pump fluid from the first chamber and into the second chamber, thereby causing the delivery fluid to be expelled out of the first outlet.

### Claim 11 (depends on 1)

The fluid delivery system of claim 1, wherein the storage liquid is a different fluid than the pump liquid.

### Claim 12 (depends on 1)

The fluid delivery system of claim 1, wherein the storage liquid and the pump liquid comprise the same fluid.

### Claim 13 (depends on 1)

The fluid delivery system of claim 1, wherein the pump liquid is an electrolyte.

### Claim 14 (depends on 1)

The fluid delivery system of claim 1, wherein the second moveable pump element is within the housing.
