# US 8,788,283 B2 · Modifiable attribute identification

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 8,788,283 B2
- Document ID: US8788283B2
- Status: Granted
- Kind: B2
- Application number: 13/464,554
- Filed: 2012-05-04
- Published: 2012-08-30
- Granted: 2014-07-22
- Earliest claimed: 2007-03-16
- Assignees: Expanse Bioinformatics, Inc.
- Applicants: Andrew Alexander Kenedy; Charles Anthony Eldering
- Inventors: Andrew Alexander Kenedy; Charles Anthony Eldering
- Web page: https://patentgrep.com/patent/US8788283B2

## CPC

- G16H 70/20: relating to practices or guidelines
- G06F 16/00: Information retrieval; Database structures therefor; File system structures therefor
- G06F 16/2282: {Tablespace storage structures; Management thereof}
- G06F 16/24575: {using context}
- G06F 16/24578: {using ranking}
- G06F 16/285: {Clustering or classification}
- G06F 16/951: Indexing; Web crawling techniques
- G06F 16/9535: Search customisation based on user profiles and personalisation
- G06F 16/9538: Presentation of query results
- G06F 16/955: using information identifiers, e.g. uniform resource locators [URL]
- G06N 5/04: Inference or reasoning models
- G06N 7/01: Probabilistic graphical models, e.g. probabilistic networks
- G06Q 40/00: Finance; Insurance; Tax strategies; Processing of corporate or income taxes
- G06Q 40/08: Insurance
- G09B 19/00: Teaching not covered by other main groups of this subclass (teaching or practice apparatus for gun-aiming or gun-laying F41G3/26)
- G16B 20/00: ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B 20/20: Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
- G16B 20/40: Population genetics; Linkage disequilibrium
- G16H 20/30: relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
- G16H 40/63: for local operation
- G16H 50/30: for calculating health indices; for individual health risk assessment
- G16H 50/70: for mining of medical data, e.g. analysing previous cases of other patients
- H04L 67/306: User profiles
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N)
- G06N: COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06Q: INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G09B: EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS (devices for psychotechnics or for testing reaction times A61B5/16; games, sports, amusements A63; projectors, projector screens G03B)
- G16B: BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- H04L: TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION (arrangements common to telegraphic and telephonic communication H04M)

## Abstract

A method, software, database and system for determining modifiable lifestyle attributes which when altered, can increase the longevity of an individual is presented. Based on an individual's pangenetic (genetic and epigenetic) attributes and by comparison with databases of attributes and longevity data, specific modifiable attributes which increase longevity, based on the individual's specific pangenetic makeup, can be identified.

## Claims

### Claim 1

A non-transitory computer readable medium having computer-executable instructions for generating a pangenetic based determination of one or more modifiable lifestyle attributes for an individual, which when modified provide a recommended personalized treatment regimen for a disease, comprising:
a) a previously stored database of attribute profiles and disease data for a population of individuals, wherein each attribute profile comprises pangenetic and modifiable lifestyle attributes that are correlated with at least a portion of the disease data, the pangenetic attribute(s) further comprising genetic or epigenetic attributes; and
b) a set of instructions that, when executed by a processor, cause that processor to perform the steps of:
i) receiving a query associated with the individual and the disease;
ii) accessing an attribute profile associated with the individual, wherein the attribute profile contains pangenetic and at least one modifiable lifestyle attribute of the individual, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;
iii) determining, based on a comparison of the attribute profile of the individual and the previously stored database of attribute profiles and disease data for the population of individuals, one or more modifiable lifestyle attributes associated with the individual, which provide a personalized treatment regimen for the disease; and
iv) transmitting the one or more modifiable lifestyle attributes as output to provide the recommended personalized treatment regimen for the disease for the individual.

### Claim 2 (depends on 1)

The non-transitory computer readable medium of claim 1, further comprising a set of instructions that, when executed by a processor, cause that processor to perform the step of:
v) rank ordering the one or more modifiable lifestyle attributes in an order corresponding to those modifiable attributes that provide the most effective recommended personalized treatment regimen for the disease.

### Claim 3

A computer based method for generating a pangenetic based determination of one or more disease related modifiable lifestyle attributes for an individual, which when modified provide a recommended personalized treatment regimen for a disease, comprising:
a) receiving a query related to the individual and the disease;
b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic attributes and at least one modifiable lifestyle attribute of the individual, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;
c) accessing a previously stored database containing pangenetic and modifiable lifestyle attributes along with disease data for a population of individuals, wherein a portion of the pangenetic and modifiable lifestyle attributes are correlated with at least a portion of disease data, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;
d) determining, by comparing the attribute profile of the individual and with attributes in the previously stored database containing pangenetic and modifiable lifestyle attributes correlated with disease data for the population of individuals, one or more modifiable lifestyle attributes that when modified provide a personalized treatment regimen for the disease; and
e) transmitting the one or more modifiable lifestyle attributes as output to provide a recommended personalized treatment regimen for the disease for the individual.

### Claim 4 (depends on 3)

The computer based method of claim 3, further comprising:
f) rank ordering the one or more modifiable lifestyle attributes in an order corresponding to those modifiable attributes that provide the most effective recommended personalized treatment regimen for the disease.

### Claim 5

A system for generating a pangenetic based determination of one or more modifiable lifestyle attributes for an individual, which when modified provide a recommended personalized treatment regimen for a disease, comprising:
a) a previously stored database of attribute profiles and disease data for a population of individuals, wherein each attribute profile comprises pangenetic and modifiable lifestyle attributes correlated with at least a portion of the disease data the pangenetic attribute(s) further comprising genetic or epigenetic attributes; and
b) a processor and an associated memory, the associated memory containing a set of instructions that, when executed by a processor, cause the processor to perform the steps of:
i) receiving a query associated with an individual and the disease;
ii) accessing an attribute profile associated with the individual, wherein the attribute profile contains pangenetic and at least one modifiable lifestyle attribute of the individual, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;
iii) determining, by comparing the attribute profile of the individual with attribute profiles and disease data in the previously stored database for the population of individuals, one or more modifiable lifestyle attributes associated with the individual which when modified provide a personalized treatment regimen for the disease; and
iv) transmitting the one or more modifiable lifestyle attributes as output to provide a recommended personalized treatment regimen for the disease of the individual.

### Claim 6 (depends on 5)

The system of claim 5, further comprising a set of instructions that, when executed by a processor, cause the processor to perform the step of:
v) rank ordering the one or more modifiable lifestyle attributes in an order corresponding to those modifiable attributes that provide the most effective recommended personalized treatment regimen for the disease of the individual.