# US 8,788,007 B2 · Transcutaneous analyte sensor

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- Number: US 8,788,007 B2
- Document ID: US8788007B2
- Status: Granted
- Kind: B2
- Application number: 13/415,721
- Filed: 2012-03-08
- Published: 2012-07-05
- Granted: 2014-07-22
- Earliest claimed: 2003-08-01
- Assignees: DexCom, Inc.
- Applicants: James H. Brauker; Apurv Ullas Kamath; Paul V. Goode; Mark Brister
- Inventors: James H. Brauker; Apurv Ullas Kamath; Paul V. Goode; Mark Brister
- Web page: https://patentgrep.com/patent/US8788007B2

## CPC

- A61B 5/14865: {invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors}
- A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement}
- A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes}
- A61B 5/6833: {Adhesive patches}
- A61B 5/6848: {Needles}
- A61B 5/6849: {in combination with a needle set}
- A61B 5/0002: {Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07)}
- A61B 5/1495: Calibrating or testing of in-vivo probes
- A61B 5/726: {using Wavelet transforms}
- A61B 5/743: {Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots}
- A61B 2560/0223: of calibration, e.g. protocols for calibrating sensors
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

## Claims

### Claim 1

A method for calibrating a continuous glucose monitoring system, comprising:
positioning at least a portion of a glucose sensor in a body of a user;
obtaining a plurality of signals from the glucose sensor;
determining, using a processor, an acceleration of glucose level increase or decrease based on the obtained signal; and
determining, using the processor, whether calibration is appropriate based on the determined acceleration, wherein determining whether calibration is appropriate comprises comparing the determined acceleration to a predetermined value, and wherein, when the determined acceleration is above the predetermined value, determining that calibration is not appropriate.

### Claim 2 (depends on 1)

The method of claim 1, further comprising waiting a predetermined time period before performing calibration when it is determined that calibration is not appropriate.

### Claim 3 (depends on 1)

The method of claim 1, further comprising performing calibration using a blood sample to calibrate the signals from the glucose sensor.

### Claim 4

A method for calibrating a continuous glucose monitoring system, comprising:
positioning at least a portion of a glucose sensor in a body of a user;
obtaining a plurality of signals from the glucose sensor;
determining, using a processor, an acceleration of glucose level increase or decrease based on the obtained signal; and
determining, using the processor, whether calibration is appropriate based on the determined acceleration, wherein determining whether calibration is appropriate comprises comparing the determined acceleration to a predetermined value, and, wherein, when the determined acceleration is below the predetermined value, determining that calibration is appropriate.

### Claim 5 (depends on 4)

The method of claim 4, further comprising performing calibration using a blood sample to calibrate the signals from the glucose sensor.