# US 8,787,620 B2 · Automated crystal identification achieved via watershed segmentation

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- Number: US 8,787,620 B2
- Document ID: US8787620B2
- Status: Granted
- Kind: B2
- Application number: 13/955,029
- Filed: 2013-07-31
- Published: 2013-11-28
- Granted: 2014-07-22
- Earliest claimed: 2010-06-15
- Assignees: Koninklijke Philps N.V.
- Applicants: Koninklijke Philips N.V.
- Inventors: Thomas Laurence; Sharon X. Wang; Jerome J. Griesmer; Thomas Blaffert; Zhiqiang Hu; Steffen Renisch
- Web page: https://patentgrep.com/patent/US8787620B2

## CPC

- G01T 1/1647: {Processing of scintigraphic data (not related to a particular imaging system G01T1/2992)}
- G01T: MEASUREMENT OF NUCLEAR OR X-RADIATION (radiation analysis of materials, mass spectrometry G01N23/00; tubes for determining the presence, intensity, density or energy of radiation or particles H01J47/00)

## Abstract

A nuclear imaging system includes a crystal identification system which receives a flood image which includes a plurality of peaks, each peak responsive to radiation detected by a corresponding scintillator crystal. A crystal identification processor partitions the flood image into a plurality of candidate regions with a watershed segmentator implementing a watershed algorithm. The candidate regions are linked in an adjacency graph, and then classified as background or relevant, where relevant regions contain a peak within the watershed lines. The regions are then assigned to a crystal according to an objective function and an assignability score. A calibration processor maps the peaks to a rectangular grid.

## Claims

### Claim 1

A method for crystal identification in nuclear imaging systems, comprising:
generating a flood image which includes a plurality of peaks, each peak responsive to received radiation and corresponding to a scintillator crystal;
identifying candidate regions in the flood image with a watershed segmentator implementing a watershed transform;
assigning crystal for each candidate region; and,
aligning the identified candidate regions of the flood image according to a rectangular grid.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the identifying step includes:
generating watershed lines according to minima within the flood image to form candidate regions; and
generating an adjacency graph with an adjacency graph generator to link the candidate regions within the flood image.

### Claim 3 (depends on 1)

The method according to claim 1, wherein the assigning step includes:
assigning candidate regions with an intensity below a defined threshold as a background region.

### Claim 4 (depends on 3)

The method according to claim 3, wherein the assigning step includes:
assigning non-background candidate regions to individual crystals.

### Claim 5 (depends on 3)

The method according to claim 3, wherein the assigning step includes:
calculating an assignability score for each region;
selecting the highest assignability scored region;
assigning the selected region to a grid location with crystal coordinates; and
assigning adjacent regions according to a selected objective function.

### Claim 6 (depends on 5)

The method according to claim 5, wherein the assigning step includes:
for regions with low assignability score, selecting a combination of crystal coordinates according to the objective function.

### Claim 7 (depends on 3)

The method according to claim 3, wherein the assigning step includes:
renumbering the crystal coordinates.

### Claim 8 (depends on 1)

A non-transitory computer readable medium carrying software for controlling one or more processors to perform the method of claim 1.

### Claim 9

A crystal identification system, comprising:
an image memory which receives a flood image which includes a plurality of peaks, each peak responsive to radiation detected by a corresponding scintillator crystal;
a crystal identification processor configured to:
identify candidate regions with an identification processor implementing a watershed transform;
assign a crystal for each candidate region;
align the candidate regions according to a rectangular grid for the flood image.

### Claim 10 (depends on 9)

The crystal identification system according to claim 9, wherein the crystal identification processor is further programmed to identify the candidate regions by:
generating watershed lines with a watershed segmentator according to minima within the flood image; and
generating an adjacency graph with an adjacency graph generator to link the candidate regions within the flood image.

### Claim 11 (depends on 9)

The crystal identification system according to claim 9, wherein the crystal identification processor is further programmed to assign the candidate regions by:
assigning candidate regions having an intensity below a defined threshold as a background region.

### Claim 12 (depends on 11)

The crystal identification system according to claim 11, wherein the crystal identification processor is further programmed to assign the candidate regions by:
assigning non-background candidate regions to individual crystals.

### Claim 13 (depends on 12)

The crystal identification system according to claim 12, wherein the crystal identification processor is further programmed to assign the candidate regions by:
calculating an assignability score for each region;
selecting the highest assignability scored region;
assigning the selected region to a grid location with crystal coordinates; and
assigning adjacent regions according to a selected objective function.

### Claim 14 (depends on 13)

The crystal identification system according to claim 13, wherein the crystal identification processor is further programmed to assign the candidate regions by:
renumbering the crystal coordinates.

### Claim 15 (depends on 12)

The crystal identification system according to claim 12, wherein the crystal identification processor is further programmed to assign the candidate regions by:
for regions with a low assignability score, selecting an optimal combination according to the objective function.

### Claim 16

An apparatus for crystal identification in nuclear imaging systems with a crystal identification processor configured to:
generate a flood image;
generating watershed lines along local intensity minima within the flood image to create candidate regions;
partition the flood image into a plurality of candidate regions;
identify maxima within each candidate region;
assign the candidate regions to corresponding crystals; and
assign the identified maxima to a crystal having crystal coordinates.

### Claim 17 (depends on 16)

The apparatus according to claim 16, the crystal identification processor further configured to:
segment the flood image into candidate regions using a watershed algorithm;
generate an adjacency graph to link candidate regions);
locate a peak within each candidate region;
label each peak with x/y coordinates according to an assignability score and a defined optimality objective function;
map the adjacency graph to a rectangular template with a calibration processor; and
display the mapped adjacency graph to a user via a graphical user interface.
