# US 8,785,428 B2 · Vermin poison

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- Number: US 8,785,428 B2
- Document ID: US8785428B2
- Status: Granted
- Kind: B2
- Application number: 12/443,447
- Filed: 2007-09-28
- Published: 2010-07-01
- Granted: 2014-07-22
- Earliest claimed: 2006-09-30
- Assignees: Morvus Technology Limited
- Applicants: Richard J. Knox; Roger Melton; Philip Burke
- Inventors: Richard J. Knox; Roger Melton; Philip Burke
- Web page: https://patentgrep.com/patent/US8785428B2

## CPC

- A01N 43/44: three- or four-membered rings
- A01N 25/004: {rodenticidal}
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS

## Abstract

Use of an orally or nasally available formulation of Tretazicar for poisoning vermin. An orally available or nasally available formulation of Tretazicar, wherein in the orally available formulation the Tretazicar is protected from acid hydrolysis, and provided that the formulation is not solid Tretazicar in a gelatin capsule. A formulation of Tretazicar in which the Tretazicar is protected from acid hydrolysis, wherein the formulation is present in a liquid form. A combination of Tretazicar and bait. A method of poisoning vermin comprising making available to the vermin an orally or nasally available formulation of Tretazicar and allowing the vermin to ingest or inhale the formulation of Tretazicar.

## Claims

### Claim 1

A composition comprising Tretazicar and a bait wherein the bait comprises solid foodstuff selected from cereals, meat, dairy produce, fruit, vegetables, beans, pulses and nuts and combinations thereof, and wherein Tretazicar is the only cytotoxic ingredient in said composition.

### Claim 2 (depends on 1)

The composition of claim 1 wherein the foodstuff comprises a cereal.

### Claim 3 (depends on 2)

The composition of claim 2 wherein the cereal is wheat, oatmeal, barley, rye, rice, maize or millet.

### Claim 4 (depends on 1)

The composition of claim 1 comprising a solution of Tretazicar in said bait which is an oil mixed with the solid foodstuff.

### Claim 5 (depends on 4)

The composition of claim 4 wherein the oil is peanut oil or vegetable oil.

### Claim 6 (depends on 1)

The composition of claim 1 wherein the Tretazicar is protected from acid hydrolysis.

### Claim 7 (depends on 1)

The composition of claim 1 which is adapted to resist release of the Tretazicar until it reaches the intestine of a rat, when ingested by the rat.

### Claim 8 (depends on 7)

The composition of claim 7 wherein the Tretazicar is encapsulated in microcapsules.

### Claim 9 (depends on 8)

The composition of claim 8 wherein the microcapsules comprise a component selected from gelatin, starch, waxes cellulose acetate phthalate, polyvinyl acetate phthalate, hydroxypropyl methylcellulose phthalate, hydroxypropyl methylcellulose acetate succinate, methacrylic acid copolymers and mixtures thereof.

### Claim 10 (depends on 1)

A method of poisoning rats which comprises making available to the rat the composition of claim 1 and allowing the rats to ingest said composition.

### Claim 11 (depends on 10)

The method of claim 10 wherein the said composition is provided at a site frequented by rats.

### Claim 12 (depends on 10)

The method of claim 10 wherein the composition contains at least 100 mg of Tretazicar.

### Claim 13 (depends on 10)

The method of claim 10 wherein the Tretazicar is protected from acid hydrolysis.

### Claim 14 (depends on 10)

The method of claim 10 wherein the composition comprises a solution of Tretazicar mixed with the foodstuff.

### Claim 15 (depends on 10)

The method of claim 10 wherein the composition comprises an oil solution of Tretazicar mixed with foodstuff.

### Claim 16 (depends on 15)

The method of claim 15 wherein the oil is peanut oil or vegetable oil.

### Claim 17 (depends on 10)

The method of claim 10 wherein the composition is formulated to resist release of the Tretazicar until it reaches the intestine of a rat, when ingested by the rat.

### Claim 18 (depends on 17)

The method of claim 17 wherein the Tretazicar is encapsulated in microcapsules prior to mixing with the foodstuff.

### Claim 19 (depends on 18)

The method of claim 18 wherein the microcapsules comprise a component selected from gelatin, starch, waxes cellulose acetate phthalate, polyvinyl acetate phthalate, hydroxypropyl methylcellulose phthalate, hydroxypropyl methylcellulose acetate succinate, methacrylic acid copolymers and mixtures thereof.

### Claim 20 (depends on 1)

A kit of parts comprising the composition of claim 1 or Tretazicar and a vermin-attractive device wherein said attractive device is not a foodstuff.

### Claim 21 (depends on 20)

The kit of parts of claim 20, wherein the Tretazicar is protected from acid hydrolysis.