# US 8,785,404 B2 · Urea compounds

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- Number: US 8,785,404 B2
- Document ID: US8785404B2
- Status: Granted
- Kind: B2
- Application number: 14/035,997
- Filed: 2013-09-25
- Published: 2014-04-10
- Granted: 2014-07-22
- Earliest claimed: 2012-10-05
- Assignees: Eli Lilly and Company
- Applicants: Eli Lilly and Company
- Inventors: Fucheng Qu
- Web page: https://patentgrep.com/patent/US8785404B2

## CPC

- A61K 31/706: containing six-membered rings with nitrogen as a ring hetero atom
- A61K 31/155: Amidines ([IMAGE cpc-sch-A61K-1029.gif]), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A61K 31/70: Carbohydrates; Sugars; Derivatives thereof (sorbitol A61K31/047)
- A61P 3/10: for hyperglycaemia, e.g. antidiabetics
- C07D 487/10: Spiro-condensed systems
- C07H 17/02: Heterocyclic radicals containing only nitrogen as ring hetero atoms
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- C07H: SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS (derivatives of aldonic or saccharic acids C07C, C07D; aldonic acids, saccharic acids C07C59/105, C07C59/285; cyanohydrins C07C255/16; glycals C07D; compounds of unknown constitution C07G; polysaccharides, derivatives thereof C08B; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification C12N15/00; sugar industry C13)

## Abstract

The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof.

## Claims

### Claim 1

A compound of the formula:
or a pharmaceutically acceptable salt thereof.

### Claim 2 (depends on 1)

The compound according to claim 1 which is:

### Claim 3 (depends on 1)

A method of treating diabetes in a patient comprising administering to a patient in need of such treatment an effective amount of the compound, or pharmaceutically acceptable salt thereof, according to claim 1.

### Claim 4 (depends on 1)

A pharmaceutical composition comprising the compound or a pharmaceutically acceptable salt thereof according to claim 1 in combination with one or more pharmaceutically acceptable carriers, diluents, or excipients.