# US 8,785,370 B2 · Reactive keratin protein formulations and methods of using for revitalizing hair

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 8,785,370 B2
- Document ID: US8785370B2
- Status: Granted
- Kind: B2
- Application number: 12/421,601
- Filed: 2009-04-09
- Published: 2009-08-27
- Granted: 2014-07-22
- Earliest claimed: 2007-10-05
- Assignees: Keratin Complex Holdings, Inc.
- Applicants: Peter Coppola; Vito C. Bucario
- Inventors: Peter Coppola; Vito C. Bucario
- Web page: https://patentgrep.com/patent/US8785370B2

## CPC

- A61K 8/65: Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
- A61K 8/347: {Phenols}
- A61Q 5/00: Preparations for care of the hair
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A formulation is disclosed comprising a reactive keratin derivative. Also described are methods of making the formulation and hair treatment methods and systems that include use of the formulation. The hair treatment methods may be useful, for example, in straightening or revitalizing hair.

## Claims

### Claim 1

A formulation useful for revitalizing hair comprising a reactive ionized keratin derivative in an aqueous solution, said reactive ionized keratin derivative comprising the reaction product of ionized keratin with a reactive aldehyde, the ionized keratin having a molecular weight between about 9,000 and 25,000 daltons, the formulation further comprising a silicone compound, one or more additional conditioning agents, and an oxidizer.

### Claim 2 (depends on 1)

The formulation of claim 1, wherein the oxidizer agent comprises benzoquinone or a derivative thereof.

### Claim 3 (depends on 2)

The formulation of claim 2, wherein the oxidizer comprises p-benzoquinone.

### Claim 4 (depends on 1)

The formulation of claim 1, wherein the reactive aldehyde is selected from an aldehyde comprising one or two aldehyde groups and nine or fewer carbons.

### Claim 5 (depends on 4)

The formulation of claim 4, wherein the reactive aldehyde is selected from formol and glutaraldehyde.

### Claim 6 (depends on 5)

The formulation of claim 5, wherein the reactive aldehyde comprises formol, and wherein the formulation comprises less than 0.1% free formol.

### Claim 7 (depends on 1)

The formulation of claim 1, further comprising an effective amount of a catalyst selected from a metal oxide and a noble metal.

### Claim 8 (depends on 1)

The formulation of claim 1, wherein the ionized keratin has a molecular weight between about 12,000 and 19,000 daltons.

### Claim 9 (depends on 1)

The formulation of claim 1, wherein the keratin derivative comprises ionized keratin that has been reacted with formol.

### Claim 10 (depends on 1)

The formulation of claim 1, further comprising a thickening agent.

### Claim 11 (depends on 10)

The formulation of claim 10, wherein the thickening agent is a cationic gum and wherein the formulation has a kinematic viscosity of between about 2000 and 5000 centistokes.

### Claim 12 (depends on 1)

The formulation of claim 1, wherein the silicone compound comprises an amino functional silicone compound selected from the group consisting of aminopropyl phenyl trimethicone, amino bispropyl dimethicone, aminopropyl dimethicone, amodimethicone, amodimethicond hydroxysterate.

### Claim 13 (depends on 1)

The formulation of claim 1, wherein the silicone compound comprises a cyclomethicone-dimethicone.

### Claim 14 (depends on 13)

The formulation of claim 13, wherein the dimethicone comprises one or more of behenoxy dimethicone, C30-45 alkyl dimethicone, C24-28 alkyl dimethicone, cetyl dimethicone, dimethoxysilyl ethylenediaminopropryl dimethicone, hydroxypropyldimethicone, stearamidopropyl dimethicone, stearoxy dimethicone, stearyl dimethicone, and vinyl dimethicone.