# US 8,784,910 B2 · Antimicrobial compositions > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,784,910 B2 - Document ID: US8784910B2 - Status: Granted - Kind: B2 - Application number: 12/402,458 - Filed: 2009-03-11 - Published: 2009-07-09 - Granted: 2014-07-22 - Earliest claimed: 2002-08-12 - Assignees: Lonza Ltd. - Applicants: Patrick Jay Lutz; Olga Borokhov; Abraham Shibu - Inventors: Patrick Jay Lutz; Olga Borokhov; Abraham Shibu - Web page: https://patentgrep.com/patent/US8784910B2 ## CPC - A01N 35/02: containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals - A01N 37/06: Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof - A01N 43/08: with oxygen as the ring hetero atom - A01N 65/00: Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof (containing compounds of determined constitution A01N27/00 - A01N59/00) - A61K 8/33: containing oxygen - A61K 8/922: {of vegetable origin} - A61L 2/18: Liquid substances - A61P 31/04: Antibacterial agents - A61Q 5/02: Preparations for cleaning the hair - A61Q 17/005: {Antimicrobial preparations} - A61Q 19/10: Washing or bathing preparations - C11D 3/2075: {Carboxylic acids-salts thereof} - C11D 3/2086: {Hydroxy carboxylic acids-salts thereof} - C11D 3/222: {Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin} - C11D 3/38: Products with no well-defined composition {, e.g. natural products} - C11D 3/382: Vegetable products, e.g. soya meal, wood flour, sawdust - C11D 3/48: Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions - A61K 2800/524: Preservatives - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS - C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL ## Abstract The present invention provides an antimicrobial composition comprising an antimicrobial effective amount (such as a preservative, bactericidal, and/or fungicidal effective amount) of a mixture comprising at least two of: (a) lemon grass oil; (b) cinnamaldehyde, cinnamon oil, Cinnamomum cassia, cinnamon extract, cassia leaf oil, 3,4-dihydroxycinnamic acid or salt thereof, or a mixture thereof; (c) sorbic acid, or a salt thereof; (d) erythorbic acid, or a salt thereof; (e) benzoic acid, or a salt thereof; (f) arabinogalactan, galactoarabinan, or a mixture thereof; (g) a hexahydro-iso-alpha-acid, tetrahydro-iso-alpha-acid, or a mixture thereof; (h) Achillea fragrantissima (Santolina fragrantissima Forssk., lavender cotton) oil; and (i) δ-gluconolactone. The present invention also provides a product (preferably a product other than a foodstuff, pharmaceutical, or cosmetic) comprising a preservative effective amount of cinnamaldehyde or a mixture of cinnamaldehyde and one or more alkanol-dialkyl hydantoins. ## Claims ### Claim 1 An antimicrobial composition comprising an antimicrobial effective amount of a mixture consisting essentially of: (a) benzoic acid, or a salt thereof; and (b) δ-gluconolactone, wherein the weight ratio of component (a) to component (b) is from about 0.2:1 to about 5:1. ### Claim 2 (depends on 1) The antimicrobial composition of claim 1, wherein the salt of benzoic acid is sodium benzoate. ### Claim 3 (depends on 1) The antimicrobial composition of claim 1, further comprising a solvent. ### Claim 4 (depends on 3) The antimicrobial composition of claim 3, wherein the solvent is selected from water, glycols, alcohols, and mixtures thereof. ### Claim 5 (depends on 4) The antimicrobial composition of claim 4, wherein the solvent is a mixture of water and a glycol. ### Claim 6 (depends on 5) The antimicrobial composition of claim 5, wherein the glycol is glycerin. ### Claim 7 (depends on 4) The antimicrobial composition of claim 4, wherein the solvent is a mixture of water and an alcohol. ### Claim 8 (depends on 7) The antimicrobial composition of claim 7, wherein the alcohol is ethanol. ### Claim 9 (depends on 1) The antimicrobial composition of claim 1, wherein said antimicrobial effective mixture is present at a concentration of from about 0.01 to about 2% by weight, based on 100% weight of the total composition. ### Claim 10 (depends on 1) A method of killing and/or inhibiting the growth of microorganisms on a substrate comprising applying an effective amount of the antimicrobial composition of claim 1 to the substrate. ### Claim 11 (depends on 10) The method of claim 10, wherein the microorganisms are selected from S. aureus, P. aeruginosa, E. coli, Candida albicans, Aspergillus niger and Phytophthora ramrum. ### Claim 12 (depends on 2) The antimicrobial composition of claim 2, wherein the weight ratio of δ-gluconolactone to sodium benzoate is from about 1:1 to about 5:1.