# US 8,784,433 B2 · Plugged tip delivery tube for marker placement

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- Number: US 8,784,433 B2
- Document ID: US8784433B2
- Status: Granted
- Kind: B2
- Application number: 13/458,206
- Filed: 2012-04-27
- Published: 2012-08-23
- Granted: 2014-07-22
- Earliest claimed: 2002-06-17
- Assignees: SenoRx, Inc.
- Applicants: Paul Lubock; Jason H. Safabash; Martin Shabaz; John Merritt
- Inventors: Paul Lubock; Jason H. Safabash; Martin Shabaz; John Merritt
- Web page: https://patentgrep.com/patent/US8784433B2

## CPC

- A61M 37/0069: {Devices for implanting pellets, e.g. markers or solid medicaments (for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027)}
- A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers}
- A61B 2090/3908: {Soft tissue, e.g. breast tissue}
- A61B 2090/3925: {ultrasonic}
- A61B 2090/3987: {Applicators for implanting markers}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An intracorporeal marker delivery device includes a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice. A plug is releasably secured within the inner bore. The plug may itself serve as a marker, and may be the sole marker. Markers may be positioned proximal to the plug, and may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements.

## Claims

### Claim 1

An intracorporeal marker delivery device, comprising:
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice;
at least one marker which is slidably disposed within the inner bore; and
a plug releasably secured within the inner bore distal to the at least one marker, the plug having a pair of diametrically opposed cantilever arms that defines an internal gap adjacent an end portion of the plug configured to reduce a lateral dimension of the plug when the plug is inserted into the inner bore,
wherein the end portion of the plug is a proximally diverging plug portion, and the gap extends from a proximal end of the plug into the proximally diverging plug portion, the proximally diverging plug portion being configured to resiliently engage the delivery tube within the inner bore, and
wherein the gap extends from the proximal end of the plug to a terminal expanded opening within the plug.

### Claim 2

An intracorporeal marker delivery device, comprising:
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice;
at least one marker which is slidably disposed within the inner bore;
a plug releasably secured within the inner bore distal to the at least one marker, the plug having an internal gap adjacent an end portion of the plug configured to reduce a lateral dimension of the plug when the plug is inserted into the inner bore, wherein the end portion of the plug is a distally diverging plug portion, and the gap extends from a distal end of the plug into the distally diverging plug portion, the distally diverging plug portion being configured to resiliently engage the delivery tube at the inner bore; and
an external retention element positioned in the gap at the distally diverging plug portion.

### Claim 3 (depends on 2)

The intracorporeal marker delivery device of claim 2, wherein the external retention element is a conical pin, with a tip end of the conical pin being inserted into the gap to expand apart the distally diverging plug portion.

### Claim 4 (depends on 2)

The intracorporeal marker delivery device of claim 2, wherein the external retention element is a wedge-shaped pin, with a tip end of the wedge-shaped pin being inserted into the gap to expand apart the distally diverging plug portion.

### Claim 5

An intracorporeal marker delivery device, comprising:
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice;
at least one marker which is slidably disposed within the inner bore;
a plug releasably secured within the inner bore distal to the at least one marker, the plug having a pair of diametrically opposed cantilever arms that defines an internal gap adjacent an end portion of the plug configured to reduce a lateral dimension of the plug when the plug is inserted into the inner bore; and
a radiographic marker element positioned within the plug, and with portions of the radiographic marker element being respectively positioned on opposing sides of the gap within the plug.

### Claim 6

An intracorporeal marker delivery device, comprising:
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice;
at least one marker which is slidably disposed within the inner bore; and
a plug releasably secured within the inner bore distal to the at least one marker, the plug having a pair of diametrically opposed cantilever arms that defines an internal gap adjacent an end portion of the plug configured to reduce a lateral dimension of the plug when the plug is inserted into the inner bore,
wherein the plug includes a lip portion at a distal end of the plug, the lip portion being configured to limit the extent of insertion of the plug into the inner bore through the discharge orifice.

### Claim 7 (depends on 6)

The intracorporeal marker delivery device of claim 6, wherein the lip portion is configured to engage an exterior circumferential surface of the distal tip of the delivery tube at the discharge orifice.

### Claim 8 (depends on 6)

The intracorporeal marker delivery device of claim 6, wherein the distal tip is beveled to form a beveled distal tip, and the lip portion has a beveled proximal surface configured to engage the beveled distal tip.

### Claim 9

An intracorporeal marker delivery device comprising:
a delivery tube which has a distal tip, a discharge orifice, a side wall and an inner bore extending to the discharge orifice, the delivery tube having at least one retention aperture extending into the side wall from the inner bore;
at least one marker body which is slidably disposed within the inner bore; and
a plug made of a resilient material that is positioned in the inner bore distal to the at least one marker body, the plug having a protrusion configured to engage and extend into the at least one retention aperture to releasably secure the plug to the side wall of the delivery tube.

### Claim 10 (depends on 9)

The intracorporeal marker delivery device of claim 9, wherein the at least one retention aperture is a plurality of retention apertures, the plug configured to engage the plurality of retention apertures to releasably secure the plug to the side wall of the delivery tube.

### Claim 11 (depends on 9)

The intracorporeal marker delivery device of claim 9, wherein the at least one retention aperture is in the form of a slot extending proximally from the distal tip into the side wall of the delivery tube.

### Claim 12 (depends on 9)

The intracorporeal marker delivery device of claim 9, wherein the at least one retention aperture is a plurality of retention apertures that includes a slot extending proximally from the distal tip into the side wall of the delivery tube.

### Claim 13 (depends on 9)

The intracorporeal marker delivery device of claim 9, wherein the at least one retention aperture includes a hole extending though the side wall of the delivery tube.

### Claim 14 (depends on 9)

The intracorporeal marker delivery device of claim 9, wherein the plug includes a tab configured to engage a respective retention aperture.

### Claim 15 (depends on 9)

The intracorporeal marker delivery device of claim 9, wherein the plug has a pair of spaced cantilever arms that are configured to form the internal gap adjacent the end portion of the plug, the pair of spaced cantilever arms configured to reduce the lateral dimension of the plug when the plug is inserted into the inner bore of the delivery lumen and configured to exert a lateral pressure on the inner bore of the delivery lumen after insertion into the inner bore.
