# US 8,784,371 B2 · Needleless injection device equipped with a protected reservoir

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- Number: US 8,784,371 B2
- Document ID: US8784371B2
- Status: Granted
- Kind: B2
- Application number: 12/441,944
- Filed: 2007-08-31
- Published: 2010-03-25
- Granted: 2014-07-22
- Earliest claimed: 2006-09-19
- Assignees: Crossject
- Applicants: Patrick Alexandre
- Inventors: Patrick Alexandre
- Web page: https://patentgrep.com/patent/US8784371B2

## CPC

- A61M 5/30: Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M 5/2046: {Media being expelled from injector by gas generation, e.g. explosive charge}
- A61M 2005/287: {by displacing occluding plugs}
- A61M 2005/3132: {having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

Needleless injection device (1) comprising a gas generator (2), a reservoir (5) in the form of a glass tube (6) closed by an upstream stopper (7) and a downstream stopper (8) between which a liquid active principle (9) is accommodated, and an injection nozzle (15) equipped with a receptacle (19) and with at least one peripheral injection conduit (20), said tube (6) having, at one of its ends, a flange (4) via which it is in contact with said nozzle (15). The main feature of this needleless injection device (1) is that the tube (6) has a cylindrical inner channel with an upstream part (21) which is continued by a downstream part (22) of smaller diameter, said downstream part (22) being surrounded by said flange (4) and opening into the receptacle (19).

## Claims

### Claim 1

A needleless injection device comprising:
a gas generator;
a reservoir constituted by a glass tube blocked by an upstream stopper and a downstream stopper, between which a liquid active principle is housed, and
an injection nozzle equipped with a receptacle and with at least one peripheral injection duct,
wherein said glass tube possesses, at one end, a flange by means of which said glass tube is in contact with said injection nozzle, said flange being a region of larger diameter of said glass tube; and
wherein said glass tube has an internal channel comprising an upstream part extended by a downstream part of smaller diameter, said downstream part being surrounded by said flange and opening into the receptacle.

### Claim 2 (depends on 1)

The needleless injection device as claimed in claim 1, wherein the internal channel has a convergent part separating the upstream part from the downstream part.

### Claim 3 (depends on 1)

The needleless injection device as claimed in claim 1, wherein a ratio between a diameter of the downstream part and a diameter of the upstream part is between 0.85 and 0.98.

### Claim 4 (depends on 1)

The needleless injection device as claimed in claim 1, wherein a ratio between a length of the downstream part of the internal channel and a length of the downstream stopper is between 0.5 and 2.0.

### Claim 5 (depends on 1)

The needleless injection device as claimed in claim 1, wherein a length of the downstream part is greater than or equal to a length of the flange.

### Claim 6 (depends on 5)

The needleless injection device as claimed in claim 5, wherein a ratio between a thickness of the glass tube at the upstream part and a thickness of the glass tube at the flange is less than 0.5.

### Claim 7 (depends on 5)

The needleless injection device as claimed in claim 5, wherein the ratio between the length of the flange and the thickness of the glass tube at said flange is between 0.1 and 0.8.

### Claim 8 (depends on 1)

The needleless injection device as claimed in claim 1, wherein the downstream stopper is solid and cylindrical, having a smooth external side wall and having a plane circular face at both ends.

### Claim 9 (depends on 1)

The needleless injection device as claimed in claim 1, wherein the glass tube is treated to improve strength by chemical toughening or by thermal toughening.

### Claim 10 (depends on 1)

The needleless injection device as claimed in claim 1, wherein the glass tube and the downstream stopper are siliconized.