# US 8,784,334 B2 · Systems and methods for obtaining analytes from a body > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,784,334 B2 - Document ID: US8784334B2 - Status: Granted - Kind: B2 - Application number: 12/928,160 - Filed: 2010-12-03 - Published: 2011-06-09 - Granted: 2014-07-22 - Earliest claimed: 2008-03-31 - Assignees: The Invention Science Fund I, LLC - Applicants: Dennis J. Rivet; Roderick A. Hyde - Inventors: Dennis J. Rivet; Roderick A. Hyde - Web page: https://patentgrep.com/patent/US8784334B2 ## CPC - A61B 5/150061: {Means for enhancing collection} - A61B 5/0031: {Implanted circuitry} - A61B 5/14: {Devices for taking samples of blood (hypodermic syringes A61M5/00); Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood (measuring of blood pressure A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06)} - A61B 5/14503: {invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors (A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence)} - A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes} - A61B 5/15: Devices for taking samples of blood - A61B 5/150022: {for capillary blood or interstitial fluid} - A61B 5/150221: {Valves} - A61B 5/150229: {Pumps for assisting the blood sampling} - A61B 5/150251: {Collection chamber divided into at least two compartments, e.g. for division of samples (injection syringes having more than one chamber A61M5/19; syringes for injection of two or more media A61M5/2448, A61M5/284; sample preparation for further analysis A61B5/150755)} - A61B 5/150351: {Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel} - A61B 5/150389: {Hollow piercing elements, e.g. canulas, needles, for piercing the skin} - A61B 5/150503: {Single-ended needles (hollow piercing element tip design A61B5/150396)} - A61B 5/150748: {Having means for aiding positioning of the piercing device at a location where the body is to be pierced (means for aiding positioning of devices for bringing media into the body A61M5/427, locating blood vessels A61B5/489)} - A61B 5/150755: {Blood sample preparation for further analysis, e.g. by separating blood components or by mixing} - A61B 5/150793: {Electrical or magnetic identification means} - A61B 5/150877: {with implanted devices} - A61B 5/15113: {Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button} - A61B 5/153: {Devices} specially adapted for taking samples of venous or arterial blood, e.g. with syringes - A61B 5/155: {Devices} specially adapted for continuous or multiple sampling, e.g. at predetermined intervals {(devices loaded with multiple lancets simultaneously A61B5/15146)} - A61B 5/157: {Devices} characterised by integrated means for measuring characteristics of blood - A61B 5/415: {the glands, e.g. tonsils, adenoids or thymus} - A61B 5/418: {lymph vessels, ducts or nodes} - A61B 5/6842: {by marking the skin} - A61B 5/6861: {Capsules, e.g. for swallowing or implanting} - A61N 1/325: {for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body (electrodes for external use A61N1/0428)} - A61N 2/00: Magnetotherapy - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract A method may include collecting at least one analyte from within a body, ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and receiving the ejected at least one analyte outside the body. A system may include a means for collecting at least one analyte from within a body, a means for ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and a means for receiving the ejected at least one analyte outside the body. ## Claims ### Claim 1 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body; means for receiving said at least one analyte outside said body, said receiving means including a means for charging an energy storage mechanism of said collecting means via an energy source located outside said body, located inside said body, or located both outside said body and inside said body. ### Claim 2 (depends on 1) The system of claim 1, further comprising: means for transferring said at least one analyte from said collecting means within said body to said ejecting means within said body. ### Claim 3 (depends on 2) The system of claim 2, wherein said collecting means is located distal to said ejecting means and said at least one analyte is transported to said ejecting means. ### Claim 4 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body; means for receiving said at least one analyte outside said body; and means for powering said collecting means via an energy source located outside said body, located inside said body, or located both outside said body and inside said body. ### Claim 5 (depends on 4) The system of claim 4, wherein said means for powering said collecting means via an energy source located outside said body, located inside said body, or located both outside said body and inside said body comprises: means for powering said collecting means via said means for receiving said at least one analyte outside said body. ### Claim 6 (depends on 4) The system of claim 4, further comprising: means for transmitting a location signal enabling said ejecting means to be located. ### Claim 7 (depends on 6) The system of claim 6, wherein said location signal comprises at least one of an electrical current, an electrical field, a magnetic flux, an optical signal, a radio frequency identification, an ultrasound, a vibration, an electromagnetic force, a force, or a pressure. ### Claim 8 (depends on 4) The system of claim 4, further comprising: means for sorting said at least one analyte. ### Claim 9 (depends on 4) The system of claim 4, further comprising: means for concentrating said at least one analyte. ### Claim 10 (depends on 4) The system of claim 4, further comprising: means for diluting said at least one analyte. ### Claim 11 (depends on 4) The system of claim 4, wherein said means for collecting at least one analyte from within a body comprises: means for collecting at least a portion of at least one of cells, proteins, bacteria, blood, a blood component, molecules, viruses, viral particles, pathogens, parasites, malarial parasites, oglionucleotides, lymph, a lymph component, or cerebral spinal fluid. ### Claim 12 (depends on 11) The system of claim 11, wherein said blood component comprises at least one of plasma or serum. ### Claim 13 (depends on 4) The system of claim 4, wherein said means for receiving said at least one analyte outside said body comprises: means for receiving said at least one analyte outside said body in a receiving device. ### Claim 14 (depends on 4) The system of claim 4, further comprising: means for transferring said at least one analyte from said collecting means within said body to said ejecting means within said body. ### Claim 15 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body; and means for receiving said at least one analyte outside said body, said receiving means including a means for charging an energy storage mechanism of said ejecting means via an energy source located outside said body, located inside said body, or located both outside said body and inside said body. ### Claim 16 (depends on 15) The system of claim 15, further comprising: means for transferring said at least one analyte from said collecting means within said body to said ejecting means within said body. ### Claim 17 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body; and means for receiving said at least one analyte outside said body, said receiving means including a means for powering said ejecting means via an energy source located outside said body, located inside said body, or located both outside said body and inside said body. ### Claim 18 (depends on 17) The system of claim 17, further comprising: means for transferring said at least one analyte from said collecting means within said body to said ejecting means within said body. ### Claim 19 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a microjet; and means for receiving said at least one analyte outside said body. ### Claim 20 (depends on 19) The system of claim 19, wherein said means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a microjet comprises: means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a liquid microjet. ### Claim 21 (depends on 20) The system of claim 20, wherein said means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a liquid microjet comprises: means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a pulsed liquid microjet. ### Claim 22 (depends on 19) The system of claim 19, further comprising: means for transferring said at least one analyte from said collecting means within said body to said ejecting means within said body. ### Claim 23 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body, the ejecting means including a means for generating pressure utilizing a piezoelectric pressure generating mechanism; and means for receiving said at least one analyte outside said body. ### Claim 24 (depends on 23) The system of claim 23, further comprising: means for transferring said at least one analyte from said collecting means within said body to said ejecting means within said body. ### Claim 25 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a needle originating from a subdermal location within said body; and means for receiving said at least one analyte outside said body. ### Claim 26 A system, comprising: means for collecting at least one analyte from within a body; means for ejecting said at least one analyte from said body through at least one dermal layer of said body via a needle configured to be controllably deployed and retracted, wherein said needle is located subdermally when retracted, and wherein at least a portion of said needle penetrates through said at least one dermal layer when deployed; and means for receiving said at least one analyte outside said body.