# US 8,784,328 B2 · Method of analysis of cardiac images

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- Number: US 8,784,328 B2
- Document ID: US8784328B2
- Status: Granted
- Kind: B2
- Application number: 13/262,613
- Filed: 2010-04-01
- Published: 2012-08-02
- Granted: 2014-07-22
- Earliest claimed: 2009-04-03
- Assignees: Universitetet I Stavanger
- Applicants: Trygve Eftestol; Leik Woie
- Inventors: Trygve Eftestol; Leik Woie
- Web page: https://patentgrep.com/patent/US8784328B2

## CPC

- G06T 7/0012: {Biomedical image inspection}
- G06T 7/41: based on statistical description of texture
- G06T 2207/10072: Tomographic images
- G06T 2207/10116: X-ray image
- G06T 2207/10132: Ultrasound image
- G06T 2207/20108: Interactive selection of 2D slice in a 3D data set
- G06T 2207/30048: Heart; Cardiac
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

The invention relates to a method of image analysis of a cardiac image of a human subject who has experienced a myocardial infarction. The method includes delineating an area of said image corresponding to scar tissue within myocardium, from the voxel data for said area, determining at least one value indicative of the likelihood of future cardiac arrhythmia, and optionally applying to said value a prediction matrix generated from the same value for other human subjects who have had a myocardial infarction and who have subsequently experienced cardiac arryhthmia.

## Claims

### Claim 1

A method of image analysis of a cardiac image of a human subject who has experienced a myocardial infarction, said method comprising: delineating an area of said image corresponding to scar tissue within myocardium; from the voxel data for said area, determining at least one value indicative of the likelihood of future cardiac arrhythmia, wherein said at least one value is a measure of image texture in said area or a measure of image voxel inhomogeneity in said area; and optionally applying to said value a prediction matrix generated from the same value for other human subjects who have had a myocardial infarction and who have subsequently experienced cardiac arryhthmia.

### Claim 2 (depends on 1)

A method as claimed in claim 1 wherein said image is a magnetic resonance image.

### Claim 3 (depends on 2)

A method as claimed in claim 2 wherein said prediction matrix is derived from at least two said values.

### Claim 4 (depends on 2)

A method as claimed in claim 2 wherein said prediction matrix is derived from at least three said values.

### Claim 5 (depends on 2)

A method as claimed in claim 2 wherein said prediction matrix is predictive of the likelihood of cardiac arryhthmia within 10 weeks of myocardial infarction.

### Claim 6 (depends on 1)

A method as claimed in claim 1 wherein said prediction matrix is derived from at least two said values.

### Claim 7 (depends on 1)

A method as claimed in claim 1 wherein said prediction matrix is derived from at least three said values.

### Claim 8 (depends on 1)

A method as claimed in claim 1 wherein said prediction matrix is predictive of the likelihood of cardiac arryhthmia within 10 weeks of myocardial infarction.

### Claim 9 (depends on 1)

A computer program for analysis of cardiac images according to the method of claim 1.

### Claim 10 (depends on 9)

A non-transitory data carrier having recorded thereon a computer program as claimed in claim 9.

### Claim 11 (depends on 9)

A computer programmed with a computer program as claimed in claim 9.

### Claim 12 (depends on 11)

A diagnostic imaging device incorporating a computer as claimed in claim 11.

### Claim 13 (depends on 1)

A non-transitory data carrier having recorded thereon a prediction matrix as defined in claim 1.