# US 8,783,248 B2 · Inhalation anaesthesia delivery system and method

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- Number: US 8,783,248 B2
- Document ID: US8783248B2
- Status: Granted
- Kind: B2
- Application number: 12/031,359
- Filed: 2008-02-14
- Published: 2009-02-26
- Granted: 2014-07-22
- Earliest claimed: 2007-02-23
- Assignees: General Electric Company
- Applicants: Erkki Paavo Heinonen; Tom Jak Haggblom; Henriikka Halinen
- Inventors: Erkki Paavo Heinonen; Tom Jak Haggblom; Henriikka Halinen
- Web page: https://patentgrep.com/patent/US8783248B2

## CPC

- A61M 16/01: specially adapted for anaesthetising {(A61M16/104, A61M16/18 take precedence)}
- A61M 16/104: {specially adapted for anaesthetics (A61M16/18 takes precedence)}
- A61M 16/085: {Gas sampling}
- A61M 16/0875: {Connecting tubes}
- A61M 16/18: Vaporising devices for anaesthetic preparations
- A61M 16/22: Carbon dioxide-absorbing devices {; Other means for removing carbon dioxide}(cartridges with absorbing substances for respiratory apparatus A62B19/00)
- A61M 2202/0208: Oxygen
- A61M 2202/0241: Anaesthetics; Analgesics
- A61M 2202/0283: Nitrous oxide (N2O)
- A61M 2202/0291: Xenon
- A61M 2230/435: partial O2 pressure (P-O2)
- A61M 2230/437: the anaesthetic agent concentration
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

An inhalation anesthesia delivery system and method, wherein the system includes a fresh gas feeding arrangement connected to a breathing circuit, a monitor device, a control device and an interface unit. The fresh gas feeding arrangement is configured to deliver a desired concentration of gas to the breathing circuit, the desired concentration being set by using the interface unit. The monitor device is configured to monitor gas concentrations in the breathing circuit by analyzing gases flowing in the breathing circuit, and the control device is configured to control the fresh gas feeding arrangement on the basis of the data received from the monitor device to keep the desired breathing gas concentration. The control device is also configured to monitor expired inorganic gas concentration by comparing the measured expired breathing gas concentration with the set target value and changing the fresh gas delivery accordingly to meet the target value.

## Claims

### Claim 1

An inhalation anesthesia delivery system, comprising:
a fresh gas feeding arrangement connected to a breathing circuit;
a monitor device;
a control device; and
an interface unit;
wherein the interface unit is configured to be used to input at least two set target gas concentration values including at least a set target end tidal oxygen (EtO2) concentration value and a set target end tidal volatile anesthetic agent concentration value;
the fresh gas feeding arrangement is configured to deliver a desired concentration of gas including at least a desired concentration of oxygen to the breathing circuit;
the monitor device is configured to monitor and measure at least two expired gas concentration values including an expired end tidal oxygen (EtO2) concentration value and an expired end tidal volatile anesthetic agent concentration value by analyzing expiration gases in the breathing circuit; the control device is configured to receive the at least two set target gas concentration values including the target end tidal oxygen (EtO2) concentration value and the set target end tidal volatile anesthetic agent concentration value from the interface unit, receive the at least two expired gas concentration values from the monitor device, and to provide the desired concentration of gas including at least the desired concentration of oxygen (O2) to the breathing circuit via the fresh gas feeding arrangement; and
the control device is further configured to control the at least two expired gas concentration values by comparing at least the measured expired end tidal oxygen (EtO2) concentration value with the set target end tidal oxygen (EtO2) concentration value and the measured expired end tidal volatile anesthetic agent concentration value with the set target end tidal volatile anesthetic agent concentration value, and changing the desired concentration of gas including the desired concentration of oxygen delivered to the breathing circuit accordingly to meet the at least two set target gas concentration values;
wherein, when the measured at least two expired end tidal concentration values are about equal to the at least two set target gas concentration values, the control device is further configured to reduce fresh gas flow to minimize consumption of the volatile anesthetic agent.

### Claim 2 (depends on 1)

The inhalation anesthesia delivery system of claim 1, wherein the monitor device is configured to further measure expired gas concentrations for at least one of N2O, and CO2.

### Claim 3 (depends on 1)

The inhalation anesthesia delivery system of claim 1, wherein the monitor device is configured to further measure expired gas concentrations for N2O or N2, and the control device is configured to compare the corresponding measured values to corresponding set target values.

### Claim 4 (depends on 1)

The inhalation anesthesia delivery system of claim 1, wherein the control device is also configured to monitor an SpO2 value and compare said value with an allowed minimum SpO2 value set by using the interface unit.

### Claim 5 (depends on 4)

The inhalation anesthesia delivery system of claim 4, wherein the control device is configured to receive set maximum and minimum values for fresh gas flow.

### Claim 6 (depends on 1)

The inhalation anesthesia delivery system of claim 1, wherein the control device is configured to monitor differences between the at least two end-tidal concentration values and the at least two set target gas concentration values.

### Claim 7 (depends on 1)

The inhalation anesthesia delivery system of claim 1, wherein the delivery system further comprises a ventilator.

### Claim 8 (depends on 1)

The inhalation anesthesia delivery system of claim 1, wherein the changing the fresh gas delivery is carried out by changing composition or/and flow rate.

### Claim 9

A method of operating an inhalation anesthesia delivery system, the method comprising:
inputting at least two set target gas concentration values including at least a set target end tidal oxygen (EtO2) concentration value and a set target end tidal volatile anesthetic agent concentration value into the system via an interface unit;
delivering via a fresh gas feeding arrangement a desired concentration of gas including at least a desired concentration of oxygen to a breathing circuit;
monitoring and measuring with a monitor device at least two expired gas concentration values including an expired end tidal oxygen (EtO2) concentration value and an expired end tidal volatile anesthetic agent concentration value by analyzing expiration gases flowing in the breathing circuit;
receiving via a control device the at least two set target gas concentration values from the interface unit, and the at least two expired gas concentration values from the monitor device;
providing via the control device the desired concentration of gas including at least the desired concentration of oxygen to the breathing circuit via the fresh gas feeding arrangement;
controlling with the control device the at least two expired gas concentration values by comparing the expired end tidal oxygen (EtO2) concentration value with the set target end tidal oxygen concentration (EtO2) value and the measured expired end tidal volatile anesthetic agent concentration value with the set target end tidal volatile anesthetic agent concentration value;
changing the desired concentration of fresh gas delivery to the breathing circuit including the desired concentration of oxygen (O2) delivery accordingly to meet the at least two set target gas concentration values; and
reducing fresh gas flow to minimize consumption of the volatile anesthetic agent when the measured at least two end tidal concentration values are about equal to the at least two set target gas concentration values.

### Claim 10 (depends on 9)

The method of claim 9, further comprising:
measuring expired breathing gas concentrations for at least one of N2O, and CO2.

### Claim 11 (depends on 10)

The method of claim 10, wherein the inputting step includes:
inputting at least one set target inorganic gas concentration value for any of N2O or N2.

### Claim 12 (depends on 11)

The method of claim 11, wherein the controlling step includes:
comparing the set target concentration values for N2O or N2 with corresponding measured expired gas concentration values for N2O or N2.

### Claim 13 (depends on 9)

The method of claim 9, further comprising:
monitoring an SpO2 concentration value; and
comparing said monitored SpO2 value with an allowed minimum SpO2 value.

### Claim 14 (depends on 9)

The method of claim 9, wherein differences between the measured at least two end-tidal concentration values and the at least two set target gas concentration values are monitored.

### Claim 15 (depends on 14)

The method of claim 14, wherein maximum and minimum values for fresh gas flow are set.

### Claim 16 (depends on 9)

The method of claim 9, wherein the delivery system further comprises a ventilator.

### Claim 17 (depends on 9)

The method of claim 9, wherein the changing the fresh gas delivery is carried out by changing composition or/and flow rate.
