# US 8,772,709 B2 · Assembly for an electrospray ion source > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,772,709 B2 - Document ID: US8772709B2 - Status: Granted - Kind: B2 - Application number: 13/550,061 - Filed: 2012-07-16 - Published: 2014-01-16 - Granted: 2014-07-08 - Earliest claimed: 2012-07-16 - Assignees: Bruker Daltonics, Inc. - Applicants: Roy P Moeller; Rohan Thakur; Felician Muntean; Maurizio A Splendore; Stephen Zanon - Inventors: Roy P Moeller; Rohan Thakur; Felician Muntean; Maurizio A Splendore; Stephen Zanon - Web page: https://patentgrep.com/patent/US8772709B2 ## CPC - H01J 49/10: Ion sources; Ion guns - H01J 49/165: {Electrospray ionisation} - H01J 49/167: {Capillaries and nozzles specially adapted therefor; (electrostatic spraying per se B05B5/00)} - H01J: ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS (spark-gaps H01T; electric arc lamps H05B31/00; particle accelerators H05H) ## Abstract An assembly for use in an electrospray ion source includes a capillary for guiding a flow of liquid generally containing analyte(s) of interest, which is to be electrosprayed into an ionization chamber, a first tube at least partially encasing the capillary such that a first conduit for guiding a first heatable gas is created proximate the capillary and a hollow member that has an internal evacuated space and is located at the outer circumference of the capillary such that heat transfer from the first heatable gas flowing proximate the capillary to the liquid in the capillary is impeded. The assembly provides a simple and lean/compact way of preventing excessive heat transfer to the liquid in the capillary of an electrospray ion source. ## Claims ### Claim 1 An assembly for an electrospray ion source, comprising: a capillary for guiding a flow of liquid which is to be electrosprayed into an ionization chamber; a first tube at least partially encasing the capillary such that a first conduit for guiding a first gas is created proximate the capillary; and a hollow member having an internal evacuated space and being located at an outer circumference of the capillary such that heat transfer from the first gas flowing proximate the capillary to the liquid in the capillary is impeded. ### Claim 2 (depends on 1) The assembly of claim 1, wherein the hollow member is an at least partially hollow jacket or sleeve disposed around the capillary, and the evacuated space is formed within the at least partially hollow jacket or sleeve. ### Claim 3 (depends on 1) The assembly of claim 1, wherein the hollow member is a double-layered wall of the capillary, and the evacuated space is formed within the double-layered wall. ### Claim 4 (depends on 1) The assembly of claim 1, further comprising a tubular structure containing a stagnant gas, the tubular structure being interposed between the hollow member and the outer circumference of the capillary. ### Claim 5 (depends on 4) The assembly of claim 4, further comprising a heat conductor reaching into an inner space of the tubular structure in order to contact the stagnant gas and receive heat therefrom, the heat conductor further extending upstream into a region where a substantially unheated first gas is supplied to the first conduit so that the substantially unheated first gas may contact a portion of the heat conductor directly or indirectly thereby receiving and carrying away heat which originates from the stagnant gas. ### Claim 6 (depends on 1) The assembly of claim 1, wherein the evacuated space is bordered by side walls of the hollow member, which side walls have one of a coating at an inner side for reflecting heat radiation and a radiative heat shield interposed therebetween. ### Claim 7 (depends on 1) The assembly of claim 1, wherein the first gas in the first conduit receives heat from a heat generator. ### Claim 8 (depends on 7) The assembly of claim 7, wherein the heat generator is thermally coupled to the first tube at an outer circumference thereof. ### Claim 9 (depends on 7) The assembly of claim 7, wherein the heat generator heats the first gas at a position outside the first conduit. ### Claim 10 (depends on 1) The assembly of claim 1, further comprising a second tube at least partially encasing the first tube such that a second conduit for guiding a second gas is created proximate the first tube. ### Claim 11 (depends on 10) The assembly of claim 10, wherein the second gas in the second conduit receives heat from a heat generator, and some heat is transmitted through an interface between the second conduit and the first conduit from the second heated gas to the first gas flowing through the first conduit. ### Claim 12 (depends on 10) The assembly of claim 10, wherein the first gas in the first conduit and the second gas in the second conduit simultaneously receive heat from a heat generator that is located at an interface between the first conduit and the second conduit, and is thermally coupled to the first conduit at an outer circumference thereof and to the second conduit at an inner circumference thereof. ### Claim 13 (depends on 1) The assembly of claim 1, wherein the capillary is removably disposed within one of the first tube, an evacuated sleeve, an evacuated jacket, and a tubular structure. ### Claim 14 An assembly for an electrospray ion source, comprising: a capillary for guiding a flow of liquid which is to be electrosprayed into an ionization chamber; a first tube at least partially encasing the capillary such that a first conduit for guiding a first gas is created proximate the capillary; a second tube at least partially encasing the first tube such that a second conduit for guiding a second gas is created proximate the first tube; and a hollow member having an internal evacuated space and being located at an interface between the first conduit and the second conduit such that heat transfer from the second gas flowing proximate the first tube to the first gas in the first tube is impeded. ### Claim 15 (depends on 14) The assembly of claim 14, wherein the second gas in the second conduit receives heat from a heat generator thermally coupled to the second tube at an outer circumference thereof. ### Claim 16 (depends on 14) The assembly of claim 14, wherein the second gas in the second conduit receives heat from a heat generator at a position outside the second conduit. ### Claim 17 An assembly for an electrospray ion source, comprising: a capillary for guiding a flow of liquid which is to be electrosprayed into an ionization chamber; a tube at least partially encasing the capillary such that a conduit for guiding a heatable gas is created proximate the capillary; a thermal insulation being located at an outer circumference of the capillary such that heat transfer from the heatable gas flowing proximate the capillary to the liquid in the capillary is impeded; a tubular structure containing a stagnant gas, the tubular structure being interposed between the thermal insulation and the outer circumference of the capillary; and a heat conductor reaching into an inner space of the tubular structure in order to contact the stagnant gas and receive heat therefrom, wherein the heat conductor further extends upstream into a region where a substantially unheated gas is supplied to the conduit so that the substantially unheated gas may contact a portion of the heat conductor directly or indirectly thereby receiving and carrying away heat, which originates from the stagnant gas, upon entering the conduit. ### Claim 18 (depends on 17) The assembly of claim 17, wherein the thermal insulation comprises one of an at least partially evacuated hollow sleeve or jacket, a solid layer of material with high heat resistance, and a combination thereof. ### Claim 19 (depends on 17) The assembly of claim 17, wherein at least portions of the heat conductor have a structured surface to allow for high heat transmission. ### Claim 20 An assembly for an electrospray ion source, comprising: a capillary for guiding a flow of liquid which is to be electrosprayed into an ionization chamber; a tube at least partially encasing the capillary such that a conduit for guiding a gas is created proximate the capillary; a thermal insulation being located at an outer circumference of the capillary such that heat transfer from the gas flowing proximate the capillary to the liquid in the capillary is impeded; and a heat conductor thermally contacting at least one of the thermal insulation at a radially inward side and the capillary at a radially outward side in order to receive heat therefrom, wherein the heat conductor also thermally contacts a conduit portion in a region where a substantially unheated gas is supplied to the conduit so that the substantially unheated gas may receive and carry away heat, which originates from the thermal insulation or the capillary, upon entering the conduit.