# US 8,771,936 B2 · Bacteriophage and antibacterial composition comprising the same

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- Number: US 8,771,936 B2
- Document ID: US8771936B2
- Status: Granted
- Kind: B2
- Application number: 13/621,730
- Filed: 2012-09-17
- Published: 2013-01-24
- Granted: 2014-07-08
- Earliest claimed: 2008-12-24
- Assignees: Cj Cheiljedang Corporation
- Applicants: CJ Cheiljedang Corporation
- Inventors: In Hye Kang; Min Tae Park; Young Wook Cho; Soo An Shin; Hyang Choi
- Web page: https://patentgrep.com/patent/US8771936B2

## CPC

- A61K 35/76: Viruses; Subviral particles; Bacteriophages
- A23K 10/18: of live microorganisms
- A23K 50/75: for poultry
- A61P 31/04: Antibacterial agents
- C12N 2795/10332: Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23K: FODDER
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- C12N: MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media C12Q1/00)

## Abstract

The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Salmonella typhimurium, Salmonella gallinarum, or Salmonella pullorum, a composition for the prevention or treatment of infectious diseases including salmonellosis and Salmonella food poisoning caused by Salmonella typhimurium, Fowl typhoid caused by Salmonella gallinarum, and Pullorum disease caused by Salmonella pullorum, which comprises the bacteriophage as an active ingredient, and an animal feed, drinking water, cleaner, and sanitizer which comprise the bacteriophage as an active ingredient. The present invention also provides important insights into prevention and control strategies against Salmonella infection and suggests that the use of bacteriophage can be a novel, safe, and effectively plausible alternative to antibiotics for the prevention of Salmonella infection in poultry.

## Claims

### Claim 1

A method for preventing infectious diseases caused by one or more pathogens selected from the group consisting of Salmonella typhimurium, Salmonella gallinarum and Salmonella pullorum, which comprises administering an isolated bacteriophage, which is deposited under accession number KCCM10976P, to a subject in need thereof.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the infectious disease caused by Salmonella typhimurium is salmonellosis or Salmonella food poisoning, the infectious disease caused by Salmonella gallinarum is Fowl typhoid, and the infectious disease caused by Salmonella pullorum is Pullorum disease.