# US 8,771,761 B2 · Composition for treating atopic dermatitis comprising extracts of bamboo and scutellaria

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- Number: US 8,771,761 B2
- Document ID: US8771761B2
- Status: Granted
- Kind: B2
- Application number: 13/586,741
- Filed: 2012-08-15
- Published: 2013-03-14
- Granted: 2014-07-08
- Earliest claimed: 2006-10-12
- Assignees: Unigen, Inc.
- Applicants: Sung Sick Woo; Dong Seon Kim; Young Chul Lee; Eun Jung Son
- Inventors: Sung Sick Woo; Dong Seon Kim; Young Chul Lee; Eun Jung Son
- Web page: https://patentgrep.com/patent/US8771761B2

## CPC

- A61K 36/899: Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K 36/539: Scutellaria (skullcap)
- A61P 17/00: Drugs for dermatological disorders
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 37/02: Immunomodulators
- A61P 37/08: Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotriene, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.

## Claims

### Claim 1

A method for treating allergic skin disease, comprising administering to a subject a therapeutically effective amount of a composition comprising a Bamboo extract and a Scutellaria extract, wherein the weight ratio of Bamboo extract to Scutellaria extract ranges from 1:3 to 3:1.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the Bamboo extract is a water-insoluble fraction of a 50-90% ethanol extract.

### Claim 3 (depends on 2)

The method according to claim 2, wherein the Scutellaria extract is obtained by extraction with water, methanol, ethanol or a mixture thereof.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the Bamboo extract is an ethanol-soluble fraction of a hot water extract.

### Claim 5 (depends on 4)

The method according to claim 4, wherein the Scutellaria extract is obtained by extraction with water, methanol, ethanol or a mixture thereof.

### Claim 6 (depends on 1)

The method according to claim 1, wherein the composition inhibits a release of histamine, leukotriene, or a combination thereof.

### Claim 7 (depends on 1)

The method according to claim 1, wherein the method comprises treating atopic dermatitis.

### Claim 8 (depends on 1)

The method according to claim 1, wherein the method comprises treating erythema, edema, papulation, oozing, crust, excoriation, lichenification or dryness.

### Claim 9 (depends on 1)

The method according to claim 1, wherein the method decreases transdermal moisture loss.

### Claim 10 (depends on 1)

The method according to claim 1, wherein the composition is formulated with a pharmaceutically acceptable carrier or excipient.

### Claim 11 (depends on 1)

The method according to claim 1, wherein the composition is administered topically.

### Claim 12 (depends on 1)

The method according to claim 1, wherein the composition is prepared as a gel, ointment, or emulsion.

### Claim 13 (depends on 12)

The method according to claim 12, wherein the composition is administered topically.
