# US 8,771,760 B2 · Method for the treatment of constipation

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- Number: US 8,771,760 B2
- Document ID: US8771760B2
- Status: Granted
- Kind: B2
- Application number: 13/093,911
- Filed: 2011-04-26
- Published: 2011-09-22
- Granted: 2014-07-08
- Earliest claimed: 2005-04-27
- Assignees: GW Pharma Limited
- Applicants: Geoffrey Guy; Philip Robson
- Inventors: Geoffrey Guy; Philip Robson
- Web page: https://patentgrep.com/patent/US8771760B2

## CPC

- A61K 31/658: {o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol}
- A61K 31/353: 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61P 1/10: Laxatives
- A61P 25/04: Centrally acting analgesics, e.g. opioids
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention relates to treatment of cancer related pain and constipation. Preferably the subject in need is administered a combination of the cannabinoids cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC). More preferably the cannabinoids are in a predefined ratio by weight of approximately 1:1 of CBD to THC.

## Claims

### Claim 1

A method of treatment of constipation comprising administering to a subject in need thereof a combination of the cannabinoids cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC), wherein the ratio of CBD:THC by weight is between 10:1 and 1:10, wherein the constipation is associated with opiate or opiate related drug therapy.