# US 8,771,229 B2 · Cartridge system for delivery of medicament

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- Number: US 8,771,229 B2
- Document ID: US8771229B2
- Status: Granted
- Kind: B2
- Application number: 13/308,899
- Filed: 2011-12-01
- Published: 2013-06-06
- Granted: 2014-07-08
- Earliest claimed: 2011-12-01
- Assignees: Picolife Technologies, LLC
- Applicants: Farid Amirouche; Arash N. Attar; Matthew L. Cantwell
- Inventors: Farid Amirouche; Arash N. Attar; Matthew L. Cantwell
- Web page: https://patentgrep.com/patent/US8771229B2

## CPC

- A61M 5/1413: {Modular systems comprising interconnecting elements}
- A61M 5/1422: {with double acting or multiple pistons}
- A61M 5/14224: {Diaphragm type}
- A61M 5/16827: {controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths (infusion of multiple fluids without using a controller A61M5/1407)}
- A61M 2205/12: with interchangeable cassettes forming partially or totally the fluid circuit
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A cartridge system for delivery of medicament includes as membrane placed between two disk magnets that are housed within pump body inserts. The pump body inserts having flow channels and fluid openings are between two inlet/outlet members. The inlet/outlet members each having a fluid outlet component and fluid openings are securely engaged to two reservoirs containing fluid medicaments.

## Claims

### Claim 1

A cartridge system, comprising:
a first reservoir and a second reservoir, wherein the first reservoir and the second reservoir each include a body having: a top end, a bottom end, an inner wall, and an outer wall enclosing a reservoir space; an opening formed in the top end, the opening being encircled by the outer wall and the inner wall, and the outer and inner walls projecting upwardly at the top end to form a female portion;
a first inlet/outlet member having a male portion configured to engage the female portion of the first reservoir, the first inlet/outlet member having a fluid receiving opening, a fluid discharge opening, and a fluid outlet component, the fluid receiving opening of the first inlet/outlet member in fluid communication with the first reservoir, and the fluid outlet component of the first inlet/outlet member in fluid communication with the fluid discharge opening of the first inlet/outlet member;
a second inlet/outlet member having a male portion configured to engage the female portion of the second reservoir, the second inlet/outlet member having a fluid receiving opening, a fluid discharge opening, and a fluid outlet component, the fluid receiving opening of the second inlet/outlet member in fluid communication with the second reservoir, and the fluid outlet component of the second inlet/outlet member in fluid communication with the fluid discharge opening of the second inlet/outlet member;
a first pump body insert having a fluid receiving opening, a fluid discharge opening, a plurality of inlet channels, and a plurality of outlet channels, the fluid receiving opening of the first pump body insert in fluid communication with the plurality of inlet channels of the first pump body insert, the plurality of inlet channels of the first pump body insert in fluid communication with the plurality of outlet channels of the first body insert, and the plurality of outlet channels of the first pump body insert in fluid communication with the fluid discharge opening of the first pump body insert;
a second pump body insert having a fluid receiving opening, a fluid discharge opening, a plurality of inlet channels, and a plurality of outlet channels, the fluid receiving opening of the second pump body insert in fluid communication with the plurality of inlet channels of the second pump body insert, the plurality of inlet channels of the second pump body insert in fluid communication with the plurality of outlet channels of the second pump body insert, and the plurality of outlet channels of the second pump body insert in fluid communication with the fluid discharge opening of the second pump body insert;
a pump membrane positioned between the first pump body insert and the second pump body insert; and
a plurality of magnets, at least one of the plurality of magnets having a distal end, a proximal end, and a body extending between the distal and proximal ends, and the proximal end being in contact with the pump membrane and the distal end being housed within at least one of the first and second pump body inserts,
wherein the fluid receiving opening of the first pump body insert is in fluid communication with the fluid receiving opening of the first inlet/outlet member, and the fluid discharge opening of the first pump body insert is in fluid communication with the fluid discharge opening of the first inlet/outlet member, and
wherein the fluid receiving opening of the second pump body insert is in fluid communication with the fluid receiving opening of the second inlet/outlet member, and the fluid discharge opening of the second pump body insert is in fluid communication with the fluid discharge opening of the second inlet/outlet member.

### Claim 2 (depends on 1)

The cartridge system of claim 1, further comprising:
a plurality of valve membranes, wherein at least one of the valve membranes is located between the fluid receiving opening of the first pump body insert and the first inlet/outlet member, at least one, of the valve membranes is located between the fluid receiving opening of the second pump body insert and the second inlet/outlet member, at least one of the valve membranes is located between the fluid discharge opening of the first pump body insert and the first inlet/outlet member, and at least one of the valve membranes is located between the fluid discharge opening of the second pump body insert and the second inlet/outlet member.

### Claim 3 (depends on 1)

The cartridge system of claim 1, wherein the fluid outlet component of the first inlet/outlet member and the fluid outlet component of the second inlet/outlet member each has a distal end, a proximal end, and a cylindrical body connecting the respective distal and the proximal ends, wherein the proximal end of the fluid outlet component of the first inlet/outlet member is in fluid communication with the fluid discharge opening of the first inlet/outlet member, and wherein the proximal end of the fluid outlet component of the second inlet/outlet member is in fluid communication with the fluid discharge of the second inlet/outlet member.

### Claim 4 (depends on 1)

The cartridge system of claim 1, further comprising:
a plurality of reservoir shells; and
an insulation layer provided within at least one of the plurality of reservoir shells, wherein the first reservoir and the second reservoir are each mounted within a said reservoir shell.

### Claim 5 (depends on 4)

The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the first reservoir and secures the first reservoir to the male portion of the first inlet/outlet member.

### Claim 6 (depends on 4)

The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the first reservoir, and the cap and the first reservoir are contained within at least one shell.

### Claim 7 (depends on 4)

The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the second reservoir and secures the second reservoir to the male portion of the second inlet/outlet member.

### Claim 8 (depends on 4)

The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the second reservoir near the male portion of the second inlet/outlet member.

### Claim 9 (depends on 4)

The cartridge system of claim 4, wherein the first reservoir and the second reservoir are mounted within the same reservoir shell.

### Claim 10 (depends on 4)

The cartridge system of claim 4, wherein the first reservoir and the second reservoir are mounted within different reservoir shells.

### Claim 11 (depends on 1)

The cartridge system of claim 1, wherein the first and the second reservoir are located within a housing unit.

### Claim 12 (depends on 11)

The cartridge system of claim 11, wherein the housing unit is made of Acrylonitrile Butadiene Styrene Medical Grade.

### Claim 13 (depends on 1)

The cartridge system of claim 1, wherein the first reservoir contains a first fluid medicament and the second reservoir contains a second fluid medicament.

### Claim 14 (depends on 13)

The cartridge system of claim 13, wherein the first reservoir and the second reservoir are pre-filled with the first fluid medicament and the second fluid medicament, respectively.

### Claim 15 (depends on 13)

The cartridge system of claim 13, wherein the first fluid medicament includes insulin and the second fluid medicament includes glucagon.

### Claim 16 (depends on 1)

The cartridge system of claim 1, wherein the pump membrane is prestressed and is made of silicone.

### Claim 17 (depends on 1)

The cartridge system of claim 1, wherein the plurality of magnets are made of gold-plated neodymium-iron-boron.

### Claim 18 (depends on 1)

The cartridge system of claim 1, wherein the first and second reservoirs are made of at least one material from the group consisting of silicone and Medical Grade Polyisoprene.

### Claim 19 (depends on 1)

The cartridge system of claim 1, further comprising an orifice located on at least one of the first inlet/outlet member and the second inlet/outlet member.
