# US 8,771,195 B2 · Cardiovascular analyzer > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,771,195 B2 - Document ID: US8771195B2 - Status: Granted - Kind: B2 - Application number: 13/121,692 - Filed: 2009-09-30 - Published: 2011-07-14 - Granted: 2014-07-08 - Earliest claimed: 2008-10-01 - Assignees: Irumedi Co., Ltd. - Applicants: Kwang Tae Kim; Seog San Hyeon - Inventors: Kwang Tae Kim; Seog San Hyeon - Web page: https://patentgrep.com/patent/US8771195B2 ## CPC - A61B 5/026: Measuring blood flow {(A61B3/1233, A61B3/1241 take precedence)} - A61B 5/02007: {Evaluating blood vessel condition, e.g. elasticity, compliance} - A61B 5/7278: {Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract The present invention relates to a cardiovascular diagnostic system which enables early detection of cardiovascular diseases and defines their causes. Unlike known electrocardiographs, the cardiovascular diagnosis system can further measure elastic coefficient of blood vessels (the degree of arteriosclerosis), blood vessel compliance, blood flow, and blood flow resistance and velocity in blood vessel branches of the right and left coronary arteries. The elastic coefficient shows organic changes to blood vessels. The compliance shows organic and functional changes of blood vessels simultaneously. The blood flow shows blood flow resistance. ## Claims ### Claim 1 A cardiovascular analyzer comprising: a bio-signal measurement system including a bio-signal measuring sensor unit which comprises an electrocardiogram (ECG) sensor, a phonocardiogram (PCG) sensor and one or more accelerated plethysmogram (APG) sensors, and a bio-signal reception and process unit which is connected to each of the sensors of the bio-signal measuring sensor unit for receiving and processing bio-signals measured by the sensors; and an analysis indicator calculation system including a main processing unit which is connected to the bio-signal reception and process unit for communicating and calculating biodynamic indicators of a coronary artery from the bio-signals, an input unit which is connected to the main processing unit for receiving control commends of user, and an output unit which is connected to the main processing unit for displaying the calculated results, wherein the main processing unit is configured to synthesizes an aortic arch internal pressure curve P from the bio-signals measured by the bio-signal measurement system and to calculates the biodynamic indicators from an area of the aortic arch internal pressure curve P. ### Claim 2 (depends on 1) The cardiovascular analyzer of claim 1, wherein the bio-signal reception and process unit comprises: a microcontroller which controls to process the bio-signals received from the bio-signal measuring unit and to transmit processed bio-signals to the main processing unit; a multi-signal selector which selects one of the bio-signals received from the ECG sensor, the PCG sensor and the APG sensors by a control signal of the microcontroller; a noise eliminator and signal amplifier which eliminates noises and/or controls amplification degree of the bio-signal selected by the multi-signal sensor by a control signal of the microcontroller; a signal switcher which receives the bio-signals from the noise eliminator and signal amplifier and selects one of the bio-signals to meet the control commands of the input unit or of embedded program in the main processing unit by a control signal of the microcontroller; a sample holder which samples and holds the bio-signal selected by the signal switcher by a control signal of the microcontroller; and an A/D converter which converts a holding bio-signal of the sample holder to a digital bio-signal and sends to the microcontroller by a control signal of the microcontroller. ### Claim 3 (depends on 2) The cardiovascular analyzer of claim 2, wherein each of the APG sensors is configured to obtain an APG waveform by sensing a pulse wave due to the pulsatory motion of an artery; and wherein the bio-signal measurement system is configured to obtains an ECG waveform, a PCG waveform and the APG waveform synchronously by the bio-signal measuring sensor unit. ### Claim 4 (depends on 3) The cardiovascular analyzer of claim 3, wherein one of the APG sensors is a cuff pulse wave sensor being a cuff sphygmomanometer equipped with a pressure sensor to sense the pulse wave. ### Claim 5 (depends on 4) The cardiovascular analyzer of claim 4, wherein the cuff pulse wave sensor comprises a rubber hose which is connected to an air pouch of the cuff sphygmomanometer, a branch hose which is connected to the rubber tube, and an adaptor which is connected to an exit of the branch hose; and wherein the adaptor is assembled to the pressure sensor to sense the pulse wave. ### Claim 6 (depends on 1) The cardiovascular analyzer of claim 1, wherein each of the APG sensors is configured to obtain an APG waveform by sensing a pulse wave due to the pulsatory motion of an artery; and wherein the bio-signal measurement system is configured to obtains an ECG waveform, a PCG waveform and the APG waveform synchronously by the bio-signal measuring sensor unit. ### Claim 7 (depends on 6) The cardiovascular analyzer of claim 6, wherein one of the APG sensors is a cuff pulse wave sensor being a cuff sphygmomanometer equipped with a pressure sensor to sense the pulse wave. ### Claim 8 (depends on 7) The cardiovascular analyzer of claim 7, wherein the cuff pulse wave sensor comprises a rubber hose which is connected to a air pouch of the cuff sphygmomanometer, a branch hose which is connected to the rubber tube, and an adaptor which is connected to an exit of the branch hose; and wherein the adaptor is connected to the pressure sensor sensing the pulse wave. ### Claim 9 (depends on 1) The cardiovascular analyzer of claim 1, wherein the main processing unit is programmed to carry out the steps of: (1) ordering the bio-signal measurement system to measure the bio-signals and receiving the bio-signals from the bio-signal measurement system; (2) analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms; and (3) calculating the biodynamic indicators from the area of the synthesized aortic arch internal pressure curve P and displaying the results of cardiovascular analysis. ### Claim 10 (depends on 9) The cardiovascular analyzer of claim 9, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 11 (depends on 10) The cardiovascular analyzer of claim 10, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 12 (depends on 11) The cardiovascular analyzer of claim 11, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 13 (depends on 12) The cardiovascular analyzer of claim 12, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 14 (depends on 13) The cardiovascular analyzer of claim 13, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 15 (depends on 13) The cardiovascular analyzer of claim 13, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 16 (depends on 15) The cardiovascular analyzer of claim 15, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; and wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 17 (depends on 9) The cardiovascular analyzer of claim 9, wherein step 3 comprises: calculating blood flow volumes Sl and Sr of the left and right coronary arteries from basic data including the area of the aortic arch internal pressure curve P; calculating compliances Cl and Cr and blood flow resistances Rl and Rr of the left and right coronary arteries from the aortic arch internal pressure curve P and the blood flow volumes Sl and Sr of the left and right coronary arteries; and transmitting the results of cardiovascular analysis to the output unit for showing the calculated compliances Cl and Cr and the calculated blood flow resistances Rl and Rr of the left and right coronary arteries on one C-R chart. ### Claim 18 (depends on 17) The cardiovascular analyzer of claim 17, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 19 (depends on 18) The cardiovascular analyzer of claim 18, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 20 (depends on 19) The cardiovascular analyzer of claim 19, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 21 (depends on 20) The cardiovascular analyzer of claim 20, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 22 (depends on 21) The cardiovascular analyzer of claim 21, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 23 (depends on 21) The cardiovascular analyzer of claim 21, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 24 (depends on 23) The cardiovascular analyzer of claim 23, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; and wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 25 (depends on 17) The cardiovascular analyzer of claim 17, wherein step 3 further comprises: calculating arterial stiffness Asl and Asr of the left and right coronary arteries from the blood flow volumes Sl and Sr, the compliances Cl and Cr and the blood flow resistances Rl and Rr of the left and right coronary arteries and transmitting to the output unit. ### Claim 26 (depends on 25) The cardiovascular analyzer of claim 25, wherein the arterial stiffness Asl and Asr of the left and right coronary arteries are calculated by the equations of: the arterial stiffness Asl of the left coronary artery is As l = K 3 ⁢ R l 1 0.25 C l ⁢ R l 1 ⁢ ( 1 - S l ) and the arterial stiffness Asr of the right coronary artery is Asr = K 3 ⁢ Rr 0.25 CrRr ⁢ ( 1 - S r ) where K3 is a coefficient derived from the clinics and is 0.7˜0.89. ### Claim 27 (depends on 26) The cardiovascular analyzer of claim 26, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 28 (depends on 27) The cardiovascular analyzer of claim 27, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 29 (depends on 28) The cardiovascular analyzer of claim 28, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 30 (depends on 29) The cardiovascular analyzer of claim 29, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 31 (depends on 30) The cardiovascular analyzer of claim 30, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 32 (depends on 31) The cardiovascular analyzer of claim 31, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; and wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 33 (depends on 30) The cardiovascular analyzer of claim 30, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 34 (depends on 25) The cardiovascular analyzer of claim 25, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor one of as the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 35 (depends on 34) The cardiovascular analyzer of claim 34, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 36 (depends on 35) The cardiovascular analyzer of claim 35, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 37 (depends on 36) The cardiovascular analyzer of claim 36, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 38 (depends on 37) The cardiovascular analyzer of claim 37, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 39 (depends on 37) The cardiovascular analyzer of claim 37, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 40 (depends on 39) The cardiovascular analyzer of claim 39, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; and wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 41 (depends on 17) The cardiovascular analyzer of claim 17, wherein step 3 further comprises: calculating blood flow velocities Vl and Vr of the left and right coronary arteries from the aortic arch internal pressure curve P and the compliances Cl and Cr of the left and right coronary arteries and transmitting to the output unit. ### Claim 42 (depends on 41) The cardiovascular analyzer of claim 41, wherein the blood flow velocities Vl and Vr of the left and right coronary arteries are calculated by the equations of: the blood flow velocity Vl of the left coronary artery is V l = C l A 0 ⁢ ( ⅆ p ⅆ t ) DW and the blood flow velocity Vr of the right coronary artery is Vr = C r A 0 ⁢ ( ⅆ p ⅆ t ) DW where ( ⅆ p ⅆ t ) DW = P ⁡ ( x 1 , t 2 ) - P ⁡ ( x 1 , t 1 ) t 2 - t 1 . ### Claim 43 (depends on 42) The cardiovascular analyzer of claim 42, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 44 (depends on 43) The cardiovascular analyzer of claim 43, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 45 (depends on 44) The cardiovascular analyzer of claim 44, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 46 (depends on 45) The cardiovascular analyzer of claim 45, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 47 (depends on 46) The cardiovascular analyzer of claim 46, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 48 (depends on 46) The cardiovascular analyzer of claim 46, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 49 (depends on 48) The cardiovascular analyzer of claim 48, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 50 (depends on 41) The cardiovascular analyzer of claim 41, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 51 (depends on 50) The cardiovascular analyzer of claim 50, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 52 (depends on 51) The cardiovascular analyzer of claim 51, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 53 (depends on 52) The cardiovascular analyzer of claim 52, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 54 (depends on 53) The cardiovascular analyzer of claim 53, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 55 (depends on 53) The cardiovascular analyzer of claim 53, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 56 (depends on 55) The cardiovascular analyzer of claim 55, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; and wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 57 (depends on 17) The cardiovascular analyzer of claim 17, wherein the blood flow volumes Sl and Sr, the compliances Cl and Cr and the blood flow resistances Rl and Rr of the left and right coronary arteries are calculated by the equations of: the blood flow volume Sl of the left coronary artery is S l = KA d ⁡ ( t * + Δ ⁢ ⁢ t d Δ ⁢ ⁢ t d ) , the blood flow volume Sr of the right coronary artery is Sr=K1pR2(1−υ2)1/2Pm(1+Ad/K2As)/(ρa), the compliance Cl of the left coronary artery is C l = ( S l - A d R l ) ( P * - P d ) , the compliance Cr of the right coronary artery is C r = k 2 ⁢ A S - A d P S * - P d · S r k 2 ⁢ A S + A d , the blood flow resistances Rl1 and Rl2 of the left coronary artery are R l 1 = P d - P v S l and R l 2 = P _ S v , and the blood flow resistance Rr of right coronary artery is Rr = k 2 ⁢ A S + A d Sr where Ad is an area of the aortic arch internal pressure curve P at diastole, As is an area of the aortic arch internal pressure curve P at systole, t* is a time to a point which the first-order derivative function of the aortic arch internal pressure curve P is zero at systole, υ is Poisson constant of blood vessel, R is an equivalent radius of blood vessel, Pm is an average blood pressure, ρ is a blood density, a is a propagation velocity of pulse wave, Pd is a blood pressure of the aortic arch internal pressure curve P at diastole, Ps is a blood pressure of the aortic arch internal pressure curve P at systole, P* and Ps* are blood pressure of the aortic arch internal pressure curve P at an incisura point, Pv is a blood pressure of the left coronary artery at random point, Sv is a cardiac output, and K, K1 and K2 are coefficients. ### Claim 58 (depends on 57) The cardiovascular analyzer of claim 57, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 59 (depends on 58) The cardiovascular analyzer of claim 58, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 60 (depends on 59) The cardiovascular analyzer of claim 59, wherein performance of step 1 by the main processing unit further includes the steps of (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 61 (depends on 60) The cardiovascular analyzer of claim 60, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 62 (depends on 61) The cardiovascular analyzer of claim 61, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 63 (depends on 61) The cardiovascular analyzer of claim 61, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 64 (depends on 63) The cardiovascular analyzer of claim 63, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; and wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee. ### Claim 65 (depends on 57) The cardiovascular analyzer of claim 57, wherein the coefficient K1 is related to a blood flow volume flowing from an entrance of the coronary artery to the right coronary artery and is 0.12˜0.15; wherein the coefficient K2 is a tissue internal pressure coefficient and is 0.7˜0.75; and wherein the coefficient K is calculated by K = kA · C s = kA [ ( 2 ⁢ ⁢ mP d + 1 ) · A d R - n ⁡ ( P * 2 - P d 2 ) ( P * - P d ) + m ⁡ ( P * 2 - P d 2 ) + 2 ⁢ ⁢ nP d ] where k is a coefficient related to a blood flow volume flowing from an entrance of the coronary artery to the left coronary artery and is 0.85˜0.88, A=πR2 is an equivalent area of the left coronary artery, Cs is a compliance at systole, and m and n are Cope constants. ### Claim 66 (depends on 65) The cardiovascular analyzer of claim 65, wherein analyzing waveforms from the received bio-signals in step 2 comprises: finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively; finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as one of the APG sensors of the bio-signals measurement system, which is pressurized above the systolic blood pressure; finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as one of the APG sensors of the bio-signals measurement system, and wherein the synthesis of the aortic arch internal pressure curve P is based on basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries. ### Claim 67 (depends on 66) The cardiovascular analyzer of claim 66, wherein the main processing unit is further programmed to carry out the steps of: displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before step 1; receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file; displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command, and wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race. ### Claim 68 (depends on 67) The cardiovascular analyzer of claim 67, wherein performance of step 1 by the main processing unit further includes the steps of: (1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state; (1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; (1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as one of the APG sensors of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and (1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously. ### Claim 69 (depends on 68) The cardiovascular analyzer of claim 68, wherein analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms in step 2 comprise: (2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step; (2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step; (2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and (2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step. ### Claim 70 (depends on 69) The cardiovascular analyzer of claim 69, wherein each of steps 2-2, 2-3, and 2-4 causes the main processing unit to return to step 1-1 if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, and wherein if the test command is not received, each of steps 2-2, 2-3, and 2-4 is followed by the subsequent step. ### Claim 71 (depends on 69) The cardiovascular analyzer of claim 69, wherein step 3 comprises: (3-1) displaying a result menu window and a output device icon if a result display command is received from the test and diagnosis window, otherwise, displaying a patient list in the registered patient file on the test result window and receiving a signal for selecting a patient and new information of the selected patient till receiving a command; (3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping step 3-1; and (3-3) outputting the selected menu result if an output command is received from the output device icon after displaying the selected menu result, otherwise, keeping step 3-2. ### Claim 72 (depends on 71) The cardiovascular analyzer of claim 71, wherein the result menu window comprises a Compliance-Resistance (C-R) chart; wherein the C-R chart is divided into sectors to show the coronary artery states according to the clinical results and is dotted to show the states of the left and right coronary arteries of an examinee.