# US 8,770,753 B2 · Scanning and processing using optical coherence tomography

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- Number: US 8,770,753 B2
- Document ID: US8770753B2
- Status: Granted
- Kind: B2
- Application number: 13/310,626
- Filed: 2011-12-02
- Published: 2012-06-07
- Granted: 2014-07-08
- Earliest claimed: 2010-12-03
- Assignees: Optovue, Inc.
- Applicants: Michael Hee; Jay Wei; David Huang; Qienyuan Zhou; Yonghua Zhao; Ben Jang; Tony Ko
- Inventors: Michael Hee; Jay Wei; David Huang; Qienyuan Zhou; Yonghua Zhao; Ben Jang; Tony Ko
- Web page: https://patentgrep.com/patent/US8770753B2

## CPC

- A61B 3/102: {for optical coherence tomography [OCT]}
- A61B 3/0025: {characterised by electronic signal processing, e.g. eye models}
- A61B 3/107: for determining the shape or measuring the curvature of the cornea
- A61B 3/14: Arrangements specially adapted for eye photography
- A61B 3/1225: {using coherent radiation}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data for a target measurement, and processing the OCT data to obtain the target measurement.

## Claims

### Claim 1

A method of eye examination, comprising:
acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data;
obtaining a corneal topography image; and
processing the OCT data by
obtaining a pachymetry map from the OCT data,
obtaining a corneal anterior power map from the corneal topography image,
registering the pacymetry map with the corneal anterior power map,
generating a corneal posterior surface, and
generating a total corneal power map.

### Claim 2 (depends on 1)

The method of claim 1, wherein the pachymetry map scan pattern is defined by a=1024, r=2, n=12, c=1, n*=0, and m=1.

### Claim 3 (depends on 1)

The method of claim 1, wherein the Pachymetry scan is defined by a=2048, r=4, n=16, c=2, n*=0, and m=1.

### Claim 4 (depends on 1)

The method of claim 1, wherein processing the OCT data further includes
detecting an anterior boundary;
de-wrapping OCT images from the OCT data;
detecting a posterior boundary;
computing corneal thickness; and
constructing a corneal thickness map.

### Claim 5 (depends on 1)

The method of claim 1, wherein processing the OCT data further includes
determining anterior and posterior boundary for each radial scan;
determining anterior and posterior curvatures for each radial scan;
determining anterior and posterior powers for each radial scan;
determining anterior and posterior powers for each scan;
determining the corneal power for each scan; and
determining the net corneal power.

### Claim 6

An OCT imaging system, comprising:
an OCT imager that acquires OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is one or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data;
a corneal topography imager that acquires a corneal topography image; and
a computer that processes the OCT data and the corneal topography image, the processing including
obtaining a pachymetry map from the OCT data,
obtaining a corneal anterior power map from corneal anterior image,
registering the pacymetry map with the corneal topography power map,
generating a corneal posterior surface, and
generating a total corneal power map.

### Claim 7 (depends on 6)

The system of claim 6, wherein the pachymetry map scan pattern is defined by a=1024, r=2, n=12, c=1, n*=0, and m=1.

### Claim 8 (depends on 6)

The system of claim 6, wherein the pachymetry scan is defined by a=2048, r=4, n=16, c=2, n*=0, and m=1.

### Claim 9 (depends on 6)

The system of claim 6, wherein the processing further includes
detecting an anterior boundary;
de-wrapping OCT images from the OCT data;
detecting a posterior boundary;
computing corneal thickness; and
constructing a corneal thickness map.

### Claim 10 (depends on 6)

The system of claim 6, wherein the processing further includes
determining anterior and posterior boundary for each radial scan;
determining anterior and posterior curvatures for each radial scan;
determining anterior and posterior powers for each radial scan;
determining anterior and posterior powers for each scan;
determining the corneal power for each scan; and
determining the net corneal power.