# US 8,770,201 B2 · Condom with multifunctional coating

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- Number: US 8,770,201 B2
- Document ID: US8770201B2
- Status: Granted
- Kind: B2
- Application number: 12/256,648
- Filed: 2008-10-23
- Published: 2009-04-30
- Granted: 2014-07-08
- Earliest claimed: 2007-10-26
- Assignees: GlycoBioSciences Inc.
- Applicants: Michael S. Zedalis; Beng Sim Chuah; David M. Lucas; Angela M. Shiokawa; Jose R. Siqueira; Dave Narasimhan
- Inventors: Michael S. Zedalis; Beng Sim Chuah; David M. Lucas; Angela M. Shiokawa; Jose R. Siqueira; Dave Narasimhan
- Web page: https://patentgrep.com/patent/US8770201B2

## CPC

- A61F 6/04: Condoms, sheaths or the like {, e.g. combined with devices protecting against contagion}
- A61L 31/10: Macromolecular materials
- A61L 31/14: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

Condoms having an elastomeric layer and coating containing an anhydrous warming lubricant and at least one or more ingredients dispersed therein, the coating being disposed on one or both surfaces are provided. The ingredients disposed on the elastomeric layer can be solid particles or encapsulated ingredients that are insoluble in the anhydrous warming lubricant and soluble in water. Methods of producing and using these condoms are also provided.

## Claims

### Claim 1

A condom, comprising:
an elastomeric layer having an outer surface and an inner surface; and
a coating disposed on the elastomeric layer, the coating comprising a substantially anhydrous liquid warming lubricant and a vasodilator disposed in the lubricant,
wherein the at least one vasodilator is provided as locally concentrated particles that are suspended in and not dissolved in the liquid warming lubricant and are soluble in water, resulting in a highly effective and concentrated form on a user's skin upon contact with skin-generated moisture.

### Claim 2 (depends on 1)

The condom of claim 1, wherein at least one of the locally concentrated particles is encapsulated.

### Claim 3 (depends on 2)

The condom of claim 2, wherein the at least one locally concentrated particle is encapsulated in a water soluble capsule shell of gelatin, hydroxyalkyl cellulose, or combination thereof.

### Claim 4 (depends on 1)

The condom of claim 1, wherein the warming lubricant comprises a glycerin, a polyhydric alcohol and non-ionic detergent in amounts effective to warm upon contact with skin-generated moisture.

### Claim 5 (depends on 4)

The condom of claim 4, wherein the warming lubricant comprises substantially equal amounts of glycerin and a polyhydric alcohol.

### Claim 6 (depends on 1)

The condom of claim 1, wherein a localized concentration of the at least one vasodilator is greater than the concentration of the vasodilator in the overall coating.

### Claim 7 (depends on 1)

The condom of claim 1, wherein the warming lubricant comprises glycerin, propylene glycol, and a surfactant and the at least one vasodilator comprises at least one of niacin, ginger, L-arginine, or a nitric oxide precursor.

### Claim 8 (depends on 1)

The condom of claim 1, wherein at least one of the locally concentrated particles is in solid phase.

### Claim 9 (depends on 1)

The condom of claim 1, wherein the coating is disposed on the inner surface, the outer surface, or both.

### Claim 10 (depends on 1)

The condom of claim 1, wherein the elastomeric layer is comprises of material selected from a group comprising natural rubber latex, synthetic polyisoprene, guayule, polyurethane, combinations thereof and copolymers thereof.

### Claim 11 (depends on 1)

The condom of claim 1, wherein the coating further comprises a menthol component or a citric acid.

### Claim 12 (depends on 1)

The condom of claim 1, wherein the condom is provided in a suitable package.

### Claim 13

A condom, comprising:
an elastomeric layer having an outer surface and an inner surface; and
a coating disposed on one or both surfaces of the elastomeric layer, the coating comprising a substantially anhydrous liquid warming lubricant and an unencapsulated L-arginine component that is suspended in and not dissolved in the liquid warming lubricant and soluble in water and in a locally concentrated form,
wherein the liquid warming lubricant and the L-arginine component together produce an enhanced effect upon contact with body moisture as compared to the use of the L-arginine component without the presence of the liquid warming lubricant.

### Claim 14 (depends on 13)

The condom of claim 13, wherein the coating further comprises a menthol component or a citric acid.

### Claim 15 (depends on 13)

The condom of claim 13, wherein the warming lubricant comprises substantially equal amounts of glycerin and a polyhydric alcohol.

### Claim 16 (depends on 13)

The condom of claim 13, wherein the L-arginine component is provided in a solid phase.

### Claim 17

A method of manufacturing a condom comprising:
forming an elastomeric layer having an outer surface and an inner surface in the shape of a condom, wherein the elastomeric layer comprises a material selected from a group consisting of natural rubber latex, synthetic polyisoprene, guayule, polyurethane, combinations thereof or copolymers thereof; and
disposing a coating on the inner surface, the outer surface, or both of the elastomeric layer, the coating comprising a substantially anhydrous liquid warming lubricant and at least one vasodilator, disposed in the lubricant, the at least one vasodilator being provided in a locally concentrated form that is suspended in and not dissolved in the liquid warming lubricant and soluble in water;
wherein the warming lubricant and the at least one vasodilator together produce an enhanced effect upon contact of both with skin-generated moisture as compared with the use of the at least one vasodilator without the presence of the liquid warming lubricant.

### Claim 18 (depends on 17)

The method of claim 17, comprising providing the at least one vasodilator as L-arginine in an unencapsulated solid phase.

### Claim 19 (depends on 17)

The method of claim 17, comprising providing the at least one vasodilator in encapsulated form.

### Claim 20 (depends on 17)

The method of claim 17, wherein the warming lubricant comprises a glycerin and a polyhydric alcohol.

### Claim 21

A condom coating comprising:
substantially anhydrous liquid warming lubricant applicable to one or more surfaces of an elastomeric condom; and
locally concentrated, water-soluble particles comprising at least one vasodilator suspended in and not dissolved in the substantially anhydrous liquid warming lubricant.

### Claim 22 (depends on 21)

The coating of claim 21, wherein the warming lubricant comprises glycerin, propylene glycol, and a surfactant.

### Claim 23 (depends on 22)

The coating of claim 22, wherein the at least one vasodilator comprises at least one of niacin, ginger, L-arginine, or a nitric oxide precursor.

### Claim 24 (depends on 21)

The coating of claim 21, wherein at least one of the particles is encapsulated.

### Claim 25 (depends on 24)

The coating of claim 24, wherein the at least one encapsulated particle is/are encapsulated in a water soluble capsule shell of gelatin, hydroxyalkyl cellulose, or combination thereof.

### Claim 26 (depends on 21)

The coating of claim 21, wherein the warming lubricant comprises a glycerin, a polyhydric alcohol and non-ionic detergent in amounts effective to warm upon contact with skin-generated moisture.

### Claim 27 (depends on 26)

The coating of claim 26, wherein the warming lubricant comprises substantially equal amounts of glycerin and a polyhydric alcohol.

### Claim 28 (depends on 21)

The coating of claim 21, wherein a localized concentration of the at least one vasodilator is greater than the concentration of the at least one vasodilator in the overall coating.

### Claim 29 (depends on 21)

The coating of claim 21, wherein at least one of the particles is in solid phase.

### Claim 30 (depends on 21)

The coating of claim 21, further comprising a menthol component or a citric acid.

### Claim 31

A condom coating comprising:
substantially anhydrous liquid warming lubricant applicable to one or more surfaces of an elastomeric condom; and
an unencapsulated locally concentrated and water-soluble L-arginine component suspended in and not dissolved in the substantially anhydrous liquid warming lubricant,
wherein the liquid warming lubricant and the L-arginine component together produce an enhanced effect upon contact with body moisture as compared to the use of the L-arginine component without the presence of the liquid warming lubricant.

### Claim 32 (depends on 31)

The coating of claim 31, further comprising a menthol component or a citric acid.

### Claim 33 (depends on 31)

The coating of claim 31, wherein the warming lubricant comprises substantially equal amounts of glycerin and a polyhydric alcohol.

### Claim 34 (depends on 31)

The coating of claim 31, wherein the L-arginine component is in a solid phase.

### Claim 35

A method of preparing a condom, the method comprising:
providing a condom having an elastomeric layer with an outer surface and an inner surface;
preparing a coating comprising suspending substantially without dissolving, in substantially anhydrous liquid warming lubricant, locally concentrated, water-soluble particles comprising at least one vasodilator; and
disposing the coating on at least one of the outer surface and the inner surface of the condom,
wherein the warming lubricant and the at least one vasodilator together produce an enhanced effect upon contact of both with skin-generated moisture as compared with the use of the at least one vasodilator without the presence of the liquid warming lubricant.

### Claim 36 (depends on 35)

The method of claim 35, wherein the elastomeric layer comprises a material selected from a group consisting of natural rubber latex, synthetic polyisoprene, guayule, polyurethane, combinations thereof, and copolymers thereof.

### Claim 37 (depends on 35)

The method of claim 35 comprising providing the at least one vasodilator as L-arginine in an unencapsulated solid phase.

### Claim 38 (depends on 35)

The method of claim 35 comprising providing the at least one vasodilator in encapsulated form.

### Claim 39 (depends on 35)

The method of claim 35, wherein the warming lubricant comprises a glycerin and a polyhydric alcohol.