# US 8,770,188 B2 · Metered dose inhaler spacer > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,770,188 B2 - Document ID: US8770188B2 - Status: Granted - Kind: B2 - Application number: 13/077,849 - Filed: 2011-03-31 - Published: 2012-10-04 - Granted: 2014-07-08 - Earliest claimed: 2011-03-31 - Assignees: CareFusion 207, Inc. - Applicants: Alex Stenzler; Steve Han - Inventors: Alex Stenzler; Steve Han - Web page: https://patentgrep.com/patent/US8770188B2 ## CPC - A61M 15/0086: {Inhalation chambers} - A61M 15/0015: {located upstream of the dispenser, i.e. not traversed by the product} - A61M 15/0018: {with exhalation check valves} - A61M 15/002: {with air flow regulating means} - A61M 15/009: {using medicine packages with incorporated spraying means, e.g. aerosol cans (pocket atomiser of the injector type A61M11/08)} - A61M 2205/3334: Measuring or controlling the flow rate - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A metered dose inhaler (MDI) spacer has a body that defines a dose receiving chamber. A proximal end portion coupled between the body and a mouth port through which a metered dose may be inhaled by a user of the MDI spacer. A distal end portion is coupled with the body. A combined one-way and flow rate control valve coupled with the distal end portion is configured for permitting external airflow into and prohibiting internal airflow out of the dose receiving chamber. A collar coupled with the distal end portion is configured for receiving an actuator shaft of a metered dose inhaler and for forming a seal about an aerosol nozzle of the metered dose inhaler such that a metered dose of medication is admissible into the dose receiving chamber via the collar while airflow into and out of the dose receiving chamber via the collar is prohibited. ## Claims ### Claim 1 A metered dose inhaler (MDI) spacer comprising: a body that defines a dose receiving chamber; a proximal end portion coupled with said body; a mouth port coupled with said proximal end portion and through which a metered dose of medication is configured to be inhaled by a user of said MDI spacer; a distal end portion coupled with said body; a combined one-way and flow rate control valve coupled with said distal end portion and configured for permitting external airflow into said dose receiving chamber and prohibiting internal airflow out of said dose receiving chamber from said distal end portion; a collar coupled with said distal end portion and configured for receiving and engaging an actuator shaft of a metered dose inhaler and forming a seal about an aerosol nozzle of said metered dose inhaler such that the metered dose of medication is conducted directly into said dose receiving chamber via said collar while airflow out of said dose receiving chamber via said distal end portion is prohibited; and an annular disk having a center aperture and a plurality of apertures positioned about the center aperture, the annular disk being positioned within the body between said combined one-way and flow rate control valve and said dose receiving chamber such that external airflow is directed into the dose receiving chamber, prior to mixing with the metered dose of medication, via the plurality of apertures and the metered dose of medication is directed into the dose receiving chamber via the center aperture. ### Claim 2 (depends on 1) The MDI spacer of claim 1, wherein said collar is collapsible. ### Claim 3 (depends on 1) The MDI spacer of claim 1, wherein said collar is centered in said distal end portion. ### Claim 4 (depends on 1) The MDI spacer of claim 1, wherein said combined one-way and flow rate control valve is an exclusive intake point for air inflow into said MDI spacer in response to inhalation via said mouth port by said user during metered dose inhalation. ### Claim 5 (depends on 1) The MDI spacer of claim 1, wherein diameter sizes of said plurality of apertures are sized based upon respective distances from said combined one-way and flow rate control valve such that each of said plurality of apertures provides an equal air resistance and thus normalizes air inflow velocity across said plurality of apertures to create a flat velocity profile for inhaled air entering said dose receiving chamber. ### Claim 6 A metered dose inhaler (MDI) spacer comprising: a body that defines a dose receiving chamber; a proximal end portion coupled with said body; a mouth port coupled with said proximal end portion and through which a metered dose is configured to be inhaled by a user of said MDI spacer; a distal end portion coupled with said body; a channel that is configured to receive an actuator shaft of a metered dose inhaler and to conduct the metered dose directly from said actuator shaft into said dose receiving chamber; a combined one-way and flow rate control valve coupled with said distal end portion and configured for permitting external airflow into said dose receiving chamber and prohibiting internal airflow out of said dose receiving chamber from said distal end portion; and a flat velocity profile plate having a first opening and a plurality of through holes, the flat velocity profile plate being disposed within said body between said combined one-way and flow rate control valve and said dose receiving chamber such that external airflow is directed into the dose receiving chamber, prior to mixing with the metered dose, via the plurality of through holes and the metered dose is directed into the dose receiving chamber via the first opening. ### Claim 7 (depends on 6) The MDI spacer of claim 6, wherein said flat velocity profile plate forms a wall of a donut shaped inflow air receiving chamber. ### Claim 8 (depends on 6) The MDI spacer of claim 6, wherein the first opening comprises a central opening defined in said flat velocity profile plate and forms a portion of a sealed metered dose entrance into said dose receiving chamber. ### Claim 9 (depends on 8) The MDI spacer of claim 8, wherein said plurality of through holes are arranged around said first opening. ### Claim 10 (depends on 6) The MDI spacer of claim 6, wherein diameter sizes of said plurality of through holes are sized based upon respective distances from said combined one-way and flow rate control valve such that each of said plurality of through holes provides an equal air resistance and thus normalizes air inflow velocity across said plurality of through holes to create a flat velocity profile for inhaled air entering said dose receiving chamber. ### Claim 11 A metered dose inhaler (MDI) spacer comprising: a body that defines a dose receiving chamber; a proximal end portion coupled with said body; a mouth port coupled with said proximal end portion and through which a metered dose is configured to be inhaled from said dose receiving chamber by a user of said MDI spacer; and an expiratory valve; and an exhaled breath deflecting mechanism coupled with said mouth port in an exhaled breath airflow path and configured for deflecting and reversing exhaled breath airflow, received via said mouth port, such that said exhaled breath airflow is directed out of said MDI spacer via said expiratory valve, wherein the exhaled breath deflecting mechanism is unresisting to an inhaled breath airflow. ### Claim 12 (depends on 11) The MDI spacer of claim 11, further comprising a plurality of expiratory valves coupled with said proximal end portion. ### Claim 13 (depends on 11) The MDI spacer of claim 11, wherein said expiratory valve is configured to open only in response to deflected exhaled breath airflow. ### Claim 14 (depends on 11) The MDI spacer of claim 11, wherein said exhaled breath deflecting mechanism comprises: a concave exhaled breath airflow reflecting surface; and a conical surface exposed to inhaled breath airflow. ### Claim 15 A metered dose inhaler (MDI) spacer comprising: a body that defines a dose receiving chamber; a distal end portion coupled with said body; a combined one-way and flow rate control valve coupled with said distal end portion and configured for permitting external airflow into and prohibiting internal airflow out of said dose receiving chamber from said distal end portion; a collar coupled with said distal end portion and configured for receiving an actuator shaft of a metered dose inhaler and for forming a seal about an aerosol nozzle of said metered dose inhaler such that a metered dose of medication is admissible into said dose receiving chamber via said collar while airflow into and out of said dose receiving chamber via said collar is prohibited; a flat velocity profile plate having a central opening and a plurality of through holes positioned about the central opening, the flat velocity profile plate being disposed within said body between said combined one-way and flow rate control valve and said dose receiving chamber to form a wall of an inflow air receiving chamber such that external airflow is directed into the dose receiving chamber, prior to mixing with the metered dose, via the plurality of through holes and the metered dose of medication is directed into the dose receiving chamber via the central opening; a proximal end portion coupled with said body; a mouth port through which the metered dose of medication is configured to be inhaled from said dose receiving chamber by a user of said MDI spacer; an expiratory valve; and an exhaled breath deflecting mechanism coupled with said mouth port in an exhaled breath airflow path and configured for deflecting and reversing exhaled breath airflow, received via said mouth port, out of said MDI spacer via said expiratory valve. ### Claim 16 (depends on 15) The MDI spacer of claim 15, wherein said collar is collapsible. ### Claim 17 (depends on 15) The MDI spacer of claim 15, wherein said collar is substantially centered in said distal end portion. ### Claim 18 (depends on 15) The MDI spacer of claim 15, wherein said combined one-way and flow rate control valve is an exclusive intake point for air inflow into said MDI spacer in response to inhalation via said mouth port by said user during metered dose inhalation. ### Claim 19 (depends on 15) The MDI spacer of claim 15, wherein the central opening defined in said flat velocity profile plate is coupled with said collar to form a sealed metered dose entrance through said collar and into said dose receiving chamber. ### Claim 20 (depends on 19) The MDI spacer of claim 19, wherein diameter sizes of said plurality of through holes are sized based upon respective distances from said combined one-way and flow rate control valve such that each of said through holes provides an equal air resistance and thus normalizes air inflow velocity across said plurality of through holes to create a flat velocity profile for inhaled air entering said dose receiving chamber. ### Claim 21 (depends on 15) The MDI spacer of claim 15, wherein said expiratory valve is configured to open only in response to deflected exhaled breath airflow. ### Claim 22 (depends on 15) The MDI spacer of claim 15, wherein said exhaled breath deflecting mechanism comprises: a concave exhaled breath airflow reflecting surface; and a conical surface exposed to inhaled breath airflow. ### Claim 23 (depends on 11) The MDI spacer of claim 11, wherein the exhaled breath deflecting mechanism is substantially centered in said proximal end portion, such that said exhaled breath deflecting mechanism is within a singular inhaled breath and exhaled breath airflow path.