Adenovirus dodecahedron particles for delivery of pharmaceutical agents
AssigneeInstytut Bio Chemii I Biofizki Pan
InventorsEwa Szolajska, Jadwiga Chroboczek, Monika Zochowska
Life of this patent
Estimating the term…
Abstract
The embodiment of the invention is a virus-like particle vector, a process for the manufacture thereof, use of the virus-like particle vector and a pharmaceutical composition, which contains the virus-like particle vector. The vector is intended for the delivery of therapeutic agents into specific mammalian tissues, especially low molecular weight agents, in particular low molecular weight anti-cancer drugs into cancer tissues. More specifically, the invention relates to the virus-like particle vector, which constitutes an adenoviral dodecahedron with the therapeutic substance encapsulated or covalently linked.
Claims17
An adenoviral dodecahedron particle comprised of pentons or penton base proteins originating from a mammalian adenovirus, with at least two copies of a bleomycin glycopeptide covalently linked to the particle.
Dependencies are inferred from the claim text.