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AssigneeAjinomoto Co., Inc.
InventorsYury Ivanovich Kozlov, Akito Chinen, Hiroshi Izui, Yoshihiko Hara, Hisashi Yasueda, Konstantin Vyacheslavovich Rybak, Ekaterina Aleksandrovna Slivinskaya, Joanna Yosifovna Katashkina
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The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
A method for producing L-glutamic acid comprising cultivating a bacterium in a culture medium to produce L-glutamic acid in the culture medium and/or the bacterium, and collecting L-glutamic acid from the culture medium and/or the bacterium, wherein said bacterium is modified to have D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase activities, wherein the bacterium is selected from the group consisting of Pantoea ananatis and coryneform bacterium.
Dependencies are inferred from the claim text.