Back to results
US 8,742,102 B2Granted
Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization
AssigneePoxel
InventorsMatthias Helmreich, Claus-Peter Niesert, Daniel Cravo, Gérard Coquerel, Guillaume Levilain, Saoussen Wacharine-Antar, Pascal Cardinael
Life of this patent
Estimating the term…
Abstract
A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.
Claims13
A process for the resolution of the two optical enantiomers of a salt of a compound of formula I
- in which
- R is methyl, phenyl, 4-hydroxy-phenyl or 4-methoxyphenyl,
- Z is propanoic acid or 2,4-dichlorophenylacetic acid,
- or a tautomer thereof, by preferential crystallization.
1 more element
Dependencies are inferred from the claim text.