Anti-biofilm compositions and methods for using
AssigneeBoard of Trustees of the University of Arkansas
InventorsCassandra L. Quave, Mark S. Smeltzer, Cesar M. Compadre, Howard Hendrickson
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Abstract
The present invention provides polyphenolic compositions derived from a plant that inhibit the formation of a biofilm. Also provided are combinations that comprise at least one phenolic phytochemical and at least one antimicrobial agent that inhibit the growth of an established biofilm. Further, the present invention provides methods for inhibiting the formation and growth of biofilms.
Claims22
A method for inhibiting formation of a bacterial biofilm, the method comprising contacting a plurality of free floating bacteria with a composition comprising ellagic acid xylofuranoside, ellagic acid mannopyranoside, ellagic acid rhamnoside, or a combination thereof.
A method for inhibiting growth of an established bacterial biofilm, the method comprising contacting the established bacterial biofilm with a composition comprising ellagic acid xylofuranoside, ellagic acid mannopyranoside, ellagic acid rhamnoside, or a combination thereof and at least one antibiotic such that the biofilm has a reduced number of bacteria.
Dependencies are inferred from the claim text.