Tissue-derived mesh for orthopedic regeneration
AssigneeWarsaw Orthopedic, Inc.
InventorsPerry Geremakis, Jennifer Grasso, David Knaack, Jo-Wen Lin, Lawrence Shimp, Robert Waterman, John Winterbottom
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Abstract
An implant including a substantially cohesive aggregate comprising bone-derived particles. Cohesiveness is maintained by a member of mechanical interlocking, engagement of adjacent bone-derived particles with one another through engagement with a binding agent, thermal bonding, chemical bonding, or a matrix material in which the bone-derived particles are retained. The aggregate is shaped as a one-dimensional or two-dimensional body.
Claims11
An implant comprising a flexible porous gauze woven from a plurality of cohesive aggregate strands, each of the cohesive aggregate strands comprising bone particles and a gene activated matrix, and the bone particles of each strand are retained in a polymer matrix, the polymer matrix having a particle width from about 0.05 mm to about 150 mm.
Dependencies are inferred from the claim text.