# US 8,739,556 B2 · Cryopreservation device

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- Number: US 8,739,556 B2
- Document ID: US8739556B2
- Status: Granted
- Kind: B2
- Application number: 13/003,940
- Filed: 2008-11-11
- Published: 2011-05-26
- Granted: 2014-06-03
- Earliest claimed: 2008-10-17
- Assignees: Taiyo Nippon Sanso Corporation
- Applicants: Shigehiro Yoshimura; Hidetoshi Ohta; Mamoru Fujita
- Inventors: Shigehiro Yoshimura; Hidetoshi Ohta; Mamoru Fujita
- Web page: https://patentgrep.com/patent/US8739556B2

## CPC

- F25D 3/10: using liquefied gases, e.g. liquid air {(for cooling semiconductor devices H10W40/305)}
- A01N 1/145: Stationary or portable vessels generating cryogenic temperatures, e.g. liquid nitrogen baths
- F25D 25/00: Charging, supporting, and discharging the articles to be cooled
- F25D: REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR (refrigerated showcases A47F3/04; thermally-insulated vessels for domestic use A47J41/00; refrigerated vehicles, see the appropriate subclasses of classes B60 - B64; containers with thermal insulation in general B65D81/38; heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants, or materials for the production of heat or cold by chemical reactions other than by combustion C09K5/00; thermally-insulated vessels for liquefied or solidified gases F17C; air-conditioning or air-humidification F24F; refrigeration machines, plants, or systems F25B; cooling of instruments or comparable apparatus without refrigeration G12B)
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS

## Abstract

A cryopreservation device of the present invention includes: a cryopreservation vessel; a house which houses the cryopreservation vessel; and a handling robot provided on the house, wherein the cryopreservation vessel comprises a vessel body which holds a low-temperature liquefied gas, a cap which closes an opening section of the vessel body and has a plurality of insertion holes formed to pass through in a vertical direction, and ampoule storing tools which are housed so as to be able to pass through the insertion holes of the cap, in which the ampoule storing tools are each comprised of a support pillar and a plurality of ampoule storing sections which are attached to the support pillar so as to be arrayed in a vertical direction of the support pillar, and an ampoule-putting-in/out work hole is formed in the cap so as to pass through in a vertical direction.

## Claims

### Claim 1

A cryopreservation device comprising:
a cryopreservation vessel;
a house which houses the cryopreservation vessel; and
a handling robot provided on the house, wherein
the cryopreservation vessel comprises a vessel body which holds a low-temperature liquefied gas, a cap which closes an opening section of the vessel body and has a plurality of insertion holes formed to pass through in a vertical direction, sheath tubes which are inserted into the insertion holes of the cap, and ampoule storing tools which are housed so as to be able to pass through the sheath tubes, in which the ampoule storing tools are each comprised of a support pillar and a plurality of ampoule storing sections which are attached to the support pillar so as to be arrayed in a vertical direction of the support pillar, and an ampoule-putting-in/out work hole is formed in the cap so as to pass through in a vertical direction;
the house is used to take the cryopreservation vessel therein or thereout, is adjacent to the opening section of the vessel body, and has a work table provided in the vicinity of the ampoule-putting-in/out work hole;
the handling robot comprises a gripper head, an input apparatus in which an identification management number of a certain ampoule is input, a bar-code reader which is provided on the work table of the house, and a control apparatus which controls a movement of the gripper head on the basis of the identification management number of the bar-code of the certain ampoule from the input apparatus; and
upper portions of the sheath tubes, which touch the cap, are comprised of resin pipes, and portions of the sheath tubes lower than the upper portions are comprised of stainless steel or aluminum alloy.

### Claim 2

A cryopreservation device comprising:
a cryopreservation vessel;
a house which houses the cryopreservation vessel; and
a handling robot provided on the house, wherein
the cryopreservation vessel comprises a vessel body which holds a low-temperature liquefied gas, a cap which closes an opening section of the vessel body and has a plurality of insertion holes formed to pass through in a vertical direction, sheath tubes which are inserted into the insertion holes of the cap, and ampoule storing tools are each comprised of a support pillar and a plurality of ampoule storing sections which are attached to the support pillar so as to be arrayed in a vertical direction of the support pillar, and an ampoule-putting-in/out work hole is formed in the cap so as to pass through in a vertical direction;
the house is used to take the cryopreservation vessel therein or thereout, is adjacent to the opening section of the vessel body, and has a work table provided in the vicinity of the ampoule-putting-in/out work hole; and
the handling robot comprises a gripper head, an input apparatus in which an identification management number of a certain ampoule is input, a bar-code reader which is provided on the work table of the house, and a control apparatus which controls a movement of the gripper head on the basis of the identification management number of the bar-code of the certain ampoule from the input apparatus, wherein
the two bar-code readers are provided on the work table,
an angle formed by two imaginary lines which pass through the each bar-code reader and the ampoule is within a range from 100° to 120°; and
upper portions of the sheath tubes, which touch the cap, are comprised of resin pipes, and portions of the sheath tubes lower than the upper portions are comprised of stainless steel or aluminum alloy.